SCHEMBL4352461

SCHEMBL4352461

CCC(C)[C@H](N)C1=NCC(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(=O)O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](C(C)CC)NC(=O)[C@@H](CCCN)NC2=O)C(C)CC)S1

nearest known ligand 0.86

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.86
LCK P06239 1/20 0.86
HKDC1 Q2TB90 1/20 0.78
NPY2R P49146 4/20 0.52
NPY1R P25929 2/20 0.52
NPY4R P50391 2/20 0.52
NPY5R Q15761 2/20 0.52
CSNK2A2 P19784 1/20 0.48
CSNK2B P67870 1/20 0.48
CSNK2A1 P68400 1/20 0.48
CSNK2A3 Q8NEV1 1/20 0.48
CRHR1 P34998 1/20 0.46
VEGFA P15692 6/20 0.45
BECN1 Q14457 3/20 0.45
FLT1 P17948 1/20 0.45
TCF4 P15884 1/20 0.43
CTNNB1 P35222 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1024602 1.00 EGFR (0.86) EGFRLCKHKDC1NPY2RNPY1R
SCHEMBL2274 1.00 EGFR (0.86) EGFRLCKHKDC1NPY2RNPY1R
Zinc Ion SCHEMBL29426351 0.95 HKDC1 (0.86) EGFRLCKHKDC1NPY2RNPY1R
Bacitracin SCHEMBL29603422 0.93 EGFR (1.00) EGFRLCKHKDC1NPY2RNPY1R
Bacitracin SCHEMBL20385900 0.93 EGFR (1.00) EGFRLCKHKDC1NPY2RNPY1R
SCHEMBL4352469 0.92 EGFR (0.77) EGFRLCKHKDC1NPY2RNPY1R
SCHEMBL1059374 0.92 EGFR (0.73) EGFRLCKHKDC1NPY2RNPY1R
SCHEMBL21413350 0.92 EGFR (0.73) EGFRLCKHKDC1NPY2RNPY1R
Chloramphenicol SCHEMBL28142143 0.91 EGFR (0.72) EGFRLCKHKDC1NPY2RNPY1R
SCHEMBL25547820 0.91 EGFR (0.97) EGFRLCKHKDC1NPY2RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101370453-B Compositions and methods for dermal delivery of drugs NUVO RES INC 2013-12-18 CN claimed
CN-101396335-A Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof PSIVIDA INC (US) 2009-04-01 CN claimed
CN-101370453-A Compositions and methods for dermal delivery of drugs ZARS PHARMA INC (US) 2009-02-18 CN claimed
US-20260027191-A1 COMPOSITIONS AND METHODS FOR TREATING BACTERIAL DISEASE UNIV ARIZONA (US) 2026-01-29 US disclosed
EP-4628100-A2 ANTI-VIRAL COMPOUNDS AND METHODS FOR ADMINISTRATION THEREOF Gregg, John Malcolm Hall (US) 2025-10-08 EP disclosed
US-12285413-B2 Anti-viral agents and methods for administration thereof GREGG JOHN M H (US) 2025-04-29 US disclosed
US-20250099566-A1 COMPOSITIONS AND METHODS FOR TREATING BACTERIAL DISEASE NATIONAL INSTITUTES OF HEALTH 2025-03-27 US disclosed
US-20240173456-A1 THERAPEUTIC COMPOSITIONS FOR WOUND TREATMENT ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY 2024-05-30 US disclosed
WO-2023201345-A2 COMPOSITIONS AND METHODS FOR TREATING BACTERIAL DISEASE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-10-19 WO disclosed
US-20230263778-A1 ANTI-VIRAL COMPOUNDS AND METHODS FOR ADMINISTRATION THEREOF GREGG JOHN M H (US) 2023-08-24 US disclosed
WO-2023137320-A2 COMPOSITIONS AND METHODS FOR TREATING BACTERIAL DISEASE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2023-07-20 WO disclosed
US-20090280069-A1 PROGUANIL TO TREAT SKIN/MUCOSAL DISEASES TOLMAR, INC. (US) 2009-11-12 US disclosed
CN-101513386-A Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof CONTROL DELIVERY SYS INC (US) 2009-08-26 CN disclosed
CN-101396335-A Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof PSIVIDA INC (US) 2009-04-01 CN disclosed
CN-101370453-A Compositions and methods for dermal delivery of drugs ZARS PHARMA INC (US) 2009-02-18 CN disclosed
CN-101271117-A Method for measuring content of ayfivin and its preparations by nephelometry YANXIA GAO (CN) 2008-09-24 CN disclosed
CN-101146516-A Treatment solution and method for selectively inducing detachment and/or death of lens epithelial cells to prevent posterior capsular opacification ZHANG JIN JUN (CN) 2008-03-19 CN disclosed
CN-1289067-C Film forming composition containing sucralose MCNEIL PPC INC (US) 2006-12-13 CN disclosed
CN-1438873-A Sustained release drug delivery device and methods of use and manufacture thereof CONTROL DELIVERY SYS INC (US) 2003-08-27 CN disclosed
CN-1411804-A Film forming composition containing sucralose MCNEIL PPC INC (US) 2003-04-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090280069-A1 PROGUANIL TO TREAT SKIN/MUCOSAL DISEASES PROKR1, PROKR2, MC1R EGFR 677/4885LCK 2025/4885HKDC1 3542/4885
US-20230263778-A1 ANTI-VIRAL COMPOUNDS AND METHODS FOR ADMINISTRATION THEREOF ACE2, ACE, SARS1 EGFR 1992/4885LCK 2407/4885HKDC1 1882/4885
US-20260027191-A1 COMPOSITIONS AND METHODS FOR TREATING BACTERIAL DISEASE DNMT3L, DNMT3A, DNMT1 EGFR 3305/4885LCK 3213/4885HKDC1 2983/4885
US-12285413-B2 Anti-viral agents and methods for administration thereof ACE2, ACE, MAVS EGFR 2376/4885LCK 2353/4885HKDC1 1692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.