Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19712395 | 0.91 | KMT2A (0.43) | PIK3CAPIK3CBPIK3CDPIK3CGNAPEPLD | |
| SCHEMBL19712405 | 0.85 | SRC (0.47) | SRCPIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL2129961 | 0.85 | SRC (0.45) | SRCPIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL2129958 | 0.85 | SRC (0.45) | SRCPIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL19712418 | 0.85 | SRC (0.47) | SRCPIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL19712388 | 0.85 | SRC (0.47) | SRCPIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL19712447 | 0.84 | SRC (0.46) | SRCPIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL19712423 | 0.84 | SRC (0.46) | SRCPIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL19712433 | 0.83 | SRC (0.45) | SRCPIK3CAPIK3CBPIK3CDPIK3CG | |
| SCHEMBL2133149 | 0.77 | SRC (0.49) | SRCPIK3CAPIK3CBPIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630123-B1 | SUBSTITUTED 6-AMINO-NICOTINAMIDES AS KCNQ2/3 MODULATORS | GRUENENTHAL GMBH (DE) | 2017-12-20 | — | — | EP | claimed |