Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.32 |
| ▸ | TUBB | P07437 | 5/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19712500 | 0.89 | PIK3CA (0.31) | MAOAMAOBPIK3CA | |
| SCHEMBL19712462 | 0.87 | BRD4 (0.35) | BRD4 | |
| SCHEMBL19712467 | 0.86 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL19712471 | 0.86 | CHRM3 (0.33) | CHRM3 | |
| SCHEMBL1289976 | 0.85 | MCL1 (0.37) | MAOABRD4KDM4EALDH1A1MAPT | |
| SCHEMBL19712486 | 0.85 | PIK3CA (0.35) | KDM4EALDH1A1MAPTHPGDPIK3CA | |
| SCHEMBL19712472 | 0.85 | BRD4 (0.35) | BRD4PIK3CA | |
| SCHEMBL19712470 | 0.85 | PIK3CA (0.34) | PIK3CA | |
| SCHEMBL19712469 | 0.85 | ALOX5AP (0.37) | BRD4PIK3CA | |
| SCHEMBL19712489 | 0.85 | FFAR4 (0.31) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670410-B1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | EMERGENT PRODUCT DEV GAITHERSBURG INC (US) | 2017-12-20 | — | — | EP | claimed |