Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.37 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 7/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19712457 | 0.92 | ALOX5AP (0.34) | ALOX5APFEN1PIK3CAMTOR | |
| SCHEMBL19712466 | 0.90 | KDM4E (0.34) | PIK3CAMTORTRPC6 | |
| SCHEMBL19712500 | 0.89 | PIK3CA (0.31) | PIK3CA | |
| SCHEMBL19712473 | 0.88 | MAT2A (0.34) | PIK3CAMTOR | |
| SCHEMBL19712467 | 0.86 | ALDH1A1 (0.30) | CYP3A4 | |
| SCHEMBL1290115 | 0.86 | ALOX5AP (0.38) | ALOX5APFEN1PIK3CAABL1MTOR | |
| SCHEMBL19712471 | 0.86 | CHRM3 (0.33) | — | |
| SCHEMBL19712465 | 0.86 | ALOX5AP (0.35) | ALOX5APFEN1PIK3CAABL1MTOR | |
| SCHEMBL19723577 | 0.85 | ALOX5AP (0.38) | ALOX5APFEN1PIK3CAABL1MTOR | |
| SCHEMBL19712470 | 0.85 | PIK3CA (0.34) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670410-B1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | EMERGENT PRODUCT DEV GAITHERSBURG INC (US) | 2017-12-20 | — | — | EP | claimed |