⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275888 | 0.72 | — | — | |
| SCHEMBL17410444 | 0.70 | — | — | |
| SCHEMBL5172070 | 0.70 | — | — | |
| SCHEMBL3573780 | 0.70 | — | — | |
| SCHEMBL9356587 | 0.69 | MCL1 (0.58) | — | |
| SCHEMBL9538555 | 0.69 | HMBS (0.41) | — | |
| Bromide SCHEMBL29042173 | 0.68 | — | — | |
| SCHEMBL1075072 | 0.67 | CCNC (0.38) | — | |
| SCHEMBL7995994 | 0.67 | CCNC (0.38) | — | |
| SCHEMBL20309 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611165-B1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) | 2023-08-16 | — | — | EP | disclosed |
| CN-104066727-B | Methyl fluoride -5,6- dihydro -4H- [1,3] oxazines class | 霍夫曼-拉罗奇有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-106795177-B | BACE1 inhibitors | 豪夫迈·罗氏有限公司 | 2019-04-23 | — | — | CN | disclosed |
| US-20160272884-A1 | Compensation Film and Organic Dot for Compensation Film | TORAY CHEMICAL KOREA INC. (KR) | 2016-09-22 | — | — | US | disclosed |
| CN-105899639-A | Compensation film and organic dot for compensation film | TORAY化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| WO-2015064864-A1 | COMPENSATION FILM AND ORGANIC DOT FOR COMPENSATION FILM | 도레이케미칼 주식회사 | 2015-05-07 | — | — | WO | disclosed |
| EP-1912979-B1 | PHENYL-{3-(3-(1H-PYRROL-2-YL)-[1,2,4]OXADIAZOL-5-YL]PIPERIDIN-1-YL}-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2011-06-22 | — | — | EP | disclosed |
| US-20090203737-A1 | Pyrrole Derivatives as Positive Allosteric Modulators of Metabotropic Receptors | ADDEX PHARMA SA (CH) | 2009-08-13 | — | — | US | disclosed |
| EP-1912979-A2 | PHENYL-3-{(3-(1H-PYRROL-2-YL)-[1,2,4]OXADIAZOL-5-YL]PIPERIDIN-1-YL}-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX Pharma S.A. (CH) | 2008-04-23 | — | — | EP | disclosed |
| WO-2006123257-A2 | PHENYL-3-{(3-(1H-PYRROL-2-YL)-[1, 2 , 4]0XADIAZ0L-5-YL]PIPERIDIN-1-YL}-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2006-11-23 | — | — | WO | disclosed |
| US-4006160-A | Process for the synthesis of N-hydroxypyrroles, N-hydroxyimidazoles, and derivatives thereof | UNIVERSITY OF ALABAMA (US) | 1977-02-01 | — | — | US | disclosed |