⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814635 | 0.82 | — | — | |
| SCHEMBL4822601 | 0.80 | TSHR (0.46) | — | |
| SCHEMBL8518179 | 0.78 | TSHR (0.50) | — | |
| SCHEMBL6938835 | 0.78 | TSHR (0.50) | — | |
| SCHEMBL28648180 | 0.78 | — | — | |
| SCHEMBL3864874 | 0.75 | — | — | |
| SCHEMBL11290190 | 0.73 | — | — | |
| SCHEMBL21487894 | 0.73 | — | — | |
| SCHEMBL20981105 | 0.73 | — | — | |
| SCHEMBL6601699 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856342-A1 | BICYCLIC DERIVATIVES AS GABAA A5 RECEPTOR MODULATORS | Richter Gedeon Nyrt. (HU) | 2021-08-04 | — | — | EP | claimed |
| EP-3768272-A1 | JAK INHIBITORS | Liao, Xibin (US) | 2021-01-27 | — | — | EP | claimed |
| WO-2020065597-A1 | BICYCLIC DERIVATIVES AS GABAA Α5 RECEPTOR MODULATORS | RICHTER GEDEON NYRT. (HU) | 2020-04-02 | — | — | WO | claimed |
| WO-2019182924-A1 | JAK INHIBITORS | LIAO XIBIN (US) | 2019-09-26 | — | — | WO | claimed |
| CN-104725628-A | Single functional branched polyethylene glycol containing degradable radical, preparation method and biorelevant substance of single functional branched polyethylene glycol | XIAMEN SINOPEG BIOTECH CO LTD | 2015-06-24 | — | — | CN | claimed |
| CN-104530415-A | Hetero-functionalized Y-type polyethylene glycol derivative, preparation method and biologically related substance thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530413-A | Biologically related substances modified by multifunctional H-type polyethylene glycol derivative | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| CN-104530417-A | Multifunctional H-type polyethylene glycol derivative and preparation method thereof | XIAMEN SINOPEG BIOTECH INC | 2015-04-22 | — | — | CN | claimed |
| WO-2008133344-A2 | PIPERIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | WO | claimed |
| US-20080275085-A1 | Piperidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | US | claimed |
| US-5384331-A | Ketamine analogues for treatment of thrombocytopenia | GENENTECH, INC. (US) | 1995-01-24 | — | — | US | claimed |
| EP-0623343-A1 | Ketamine analogues for the treatment of thrombocytopenia | GENENTECH, INC. (US) | 1994-11-09 | — | — | EP | claimed |
| US-5250732-A | Influence replication, differentiation or maturation of platelet progenitor cells | GENENTECH, INC. (US) | 1993-10-05 | — | — | US | claimed |
| US-4960870-A | DYEING WOOL, POLYAMIDES; FIBER REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | claimed |
| US-4918183-A | Monoazo dyes, process for their preparation, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | claimed |
| EP-0142104-B1 | FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | claimed |
| EP-0144776-B1 | FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-10-11 | — | — | EP | claimed |
| US-4813972-A | USING LEVELING DYES, COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1989-03-21 | — | — | US | claimed |
| EP-0159962-B1 | FIBRE-REACTIVE CHROMIUM OR COBALT COMPLEXES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-02-08 | — | — | EP | claimed |
| US-4678851-A | FIBER-RACTIVE | CIBA-GEIGY CORPORATION (US) | 1987-07-07 | — | — | US | claimed |