Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 5/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518179 | 1.00 | TSHR (0.50) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL4822601 | 0.97 | TSHR (0.46) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL7814635 | 0.90 | — | — | |
| SCHEMBL9185106 | 0.81 | ALDH1A1 (0.50) | TSHRFAAHALDH1A1LMNATP53 | |
| SCHEMBL5461072 | 0.81 | ALDH1A1 (0.50) | TSHRFAAHALDH1A1LMNATP53 | |
| SCHEMBL27565159 | 0.80 | ALDH1A1 (0.39) | FAAHALDH1A1LMNATP53NLRP3 | |
| SCHEMBL1971344 | 0.78 | — | — | |
| SCHEMBL8005897 | 0.78 | TSHR (0.48) | TSHRALDH1A1LMNATP53 | |
| SCHEMBL8072036 | 0.78 | TSHR (0.48) | TSHRALDH1A1LMNATP53 | |
| SCHEMBL8077519 | 0.78 | TSHR (0.48) | TSHRALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275006-A2 | PROTEOMIC ANALYSIS USING ACTIVITY-BASED PROBE LIBRARIES | The Scripps Research Institute (US) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001077668-A2 | PROTEOMIC ANALYSIS USING ACTIVE-SITE DIRECTED PROBES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2001-10-18 | — | — | WO | disclosed |
| WO-2001077684-A2 | PROTEOMIC ANALYSIS USING ACTIVITY-BASED PROBE LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2001-10-18 | — | — | WO | disclosed |