⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4822601 | 0.92 | TSHR (0.46) | — | |
| SCHEMBL8518179 | 0.90 | TSHR (0.50) | — | |
| SCHEMBL6938835 | 0.90 | TSHR (0.50) | — | |
| SCHEMBL1971344 | 0.82 | — | — | |
| SCHEMBL6674179 | 0.78 | — | — | |
| SCHEMBL27848611 | 0.76 | — | — | |
| SCHEMBL8485859 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL7819862 | 0.76 | — | — | |
| SCHEMBL3913999 | 0.75 | ALDH1A1 (0.46) | — | |
| SCHEMBL777321 | 0.75 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116725019-A | Methanesulfonyl bacteria azole suspending agent and preparation method thereof | 贵州大学 | 2023-09-12 | — | — | CN | disclosed |
| US-20190100515-A1 | 8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2019-04-04 | — | — | US | disclosed |
| EP-0891353-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-08-08 | — | — | EP | disclosed |
| EP-0891353-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036892-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1996039137-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-12-12 | — | — | WO | disclosed |
| US-4110322-A | SENILITY, MENTAL PERFORMANCE STIMULANTS | AKZONA INCORPORATED (US) | 1978-08-29 | — | — | US | disclosed |