Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442588 | 1.00 | CYP3A4 (0.41) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL19031749 | 0.93 | CYP3A4 (0.36) | CYP3A4TDP1 | |
| SCHEMBL196880 | 0.90 | CYP3A4 (0.38) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL6328 | 0.90 | CYP3A4 (0.38) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL6445751 | 0.90 | CYP3A4 (0.38) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL10595565 | 0.89 | CYP3A4 (0.45) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL9806656 | 0.89 | CYP3A4 (0.45) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL27343 | 0.89 | CYP3A4 (0.50) | CYP3A4TDP1ESR1ESR2TSHR | |
| Hydrochloric Acid SCHEMBL8876479 | 0.88 | CYP3A4 (0.36) | CYP3A4TDP1 | |
| SCHEMBL5079169 | 0.86 | CYP3A4 (0.43) | CYP3A4TDP1ESR1ESR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 788 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768733-B | Aryl cyclic ammonium salt arylation and silicon-based method | 中国科学技术大学 | 2025-05-23 | — | — | CN | claimed |
| CN-116332882-B | Synthesis process of key intermediate of englitz | 江苏阿尔法集团福瑞药业(宿迁)有限公司 | 2025-03-18 | — | — | CN | claimed |
| WO-2025053792-A1 | COLLECTIVE SYNTHESIS OF PHANTOMOLIN FAMILY THROUGH TOTAL SYNTHESIS OF THE SESQUITERPENE LACTONE MOLEPHANTIN | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2025-03-13 | — | — | WO | claimed |
| US-20250059143-A1 | CAMPTOTHECIN DERIVATIVE INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) | 2025-02-20 | — | — | US | claimed |
| CN-115819274-B | Synthesis method of 3, 4-difluorobenzonitrile | 济宁康盛彩虹生物科技有限公司 | 2024-09-20 | — | — | CN | claimed |
| US-12071396-B2 | Method for preparing aromatic amino acid derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-08-27 | — | — | US | claimed |
| CN-118414066-A | Polymer photoelectric material modified by heptafluoroisopropyl ether side chain, and preparation method and application thereof | 上海交通大学 | 2024-07-30 | — | — | CN | claimed |
| CN-112625502-B | Ink composition, quantum dot-polymer composite, display device, and method of manufacturing the same | 三星显示有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-116987024-A | Preparation method of atazanavir intermediate | 浙江荣耀生物科技股份有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-116768733-A | Aryl cyclic ammonium salt arylation and silicon-based method | 中国科学技术大学 | 2023-09-19 | — | — | CN | claimed |
| US-20060155105-A1 | Halogenated thiophene monomer for the preparation of regioregular polythiophenes | HONEYWELL INTERNATIONAL INC. | 2006-07-13 | — | — | US | claimed |
| US-20060155134-A1 | Process for the kumada coupling reaction | HONEYWELL INTERNATIONAL INC. | 2006-07-13 | — | — | US | claimed |
| EP-1028136-B1 | A method of forming poly-(3-substituted) thiophenes | UNIV CARNEGIE MELLON (US) | 2006-05-24 | — | — | EP | claimed |
| US-20050080219-A1 | Process of preparing regioregular polymers | MERCK PATENT GMBH (DE) | 2005-04-14 | — | — | US | claimed |
| US-20040030091-A1 | Lightweight, electroconductivity, heat resistance | MCCULLOUGH RICHARD D (US) | 2004-02-12 | — | — | US | claimed |
| US-20040024171-A1 | Stereospecific electroconductive polymers such as polyhexylthiophene-polystyrene or -polymethylacrylate copolymers, used as light emitting diodes, biosensors, transistors, displays or optical apparatus | MCCULLOUGH RICHARD D (US) | 2004-02-05 | — | — | US | claimed |
| US-6602974-B1 | Conducting polymers, head-to-tail coupled regioregular polythiophenes, poly-(3-substituted) thiophene diol | CARNEGIE MELLON UNIVERSITY | 2003-08-05 | — | — | US | claimed |
| US-6166172-A | Method of forming poly-(3-substituted) thiophenes | CARNEGIE MELLON UNIVERSITY (US) | 2000-12-26 | — | — | US | claimed |
| EP-1028136-A2 | A method of forming poly-(3-substituted) thiophenes | CARNEGIE-MELLON UNIVERSITY (US) | 2000-08-16 | — | — | EP | claimed |
| US-5874628-A | Method for preparation of tertiary phosphines via nickel-catalyzed cross coupling | MONSANTO COMPANY (US) | 1999-02-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060155134-A1 | Process for the kumada coupling reaction | KMT5A, KMT5C, KCNT1 | CYP3A4 116/4885TDP1 2054/4885ESR1 3928/4885 |
| US-20250059143-A1 | CAMPTOTHECIN DERIVATIVE INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | WEE1, WEE2, ERCC4 | CYP3A4 293/4885TDP1 1064/4885ESR1 3247/4885 |
| US-12071396-B2 | Method for preparing aromatic amino acid derivative | DDC, AADAT, TYR | CYP3A4 254/4885TDP1 4450/4885ESR1 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.