Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19714778 | 0.88 | RAD51 (0.42) | APPRAD51TLR9TERTKDM4E | |
| SCHEMBL19714768 | 0.82 | SLC6A2 (0.39) | APPRAD51TLR9TERTKDM4E | |
| SCHEMBL19714789 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL31031242 | 0.77 | KDM4E (0.43) | RAD51KDM4EALDH1A1GLAGAA | |
| SCHEMBL19714762 | 0.77 | KDM4E (0.37) | APPRAD51KDM4EALDH1A1GLA | |
| SCHEMBL19714769 | 0.77 | KDM4E (0.38) | APPKDM4EALDH1A1GLAGAA | |
| SCHEMBL19714784 | 0.77 | APP (0.43) | APPRAD51KDM4EALDH1A1GLA | |
| SCHEMBL19714771 | 0.74 | RAD51 (0.32) | RAD51TLR9ALDH1A1GAAMAPT | |
| SCHEMBL19714785 | 0.74 | HTR3E (0.41) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL20307581 | 0.73 | APP (0.33) | APPTLR9TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339309-B1 | RADIOACTIVE HALOGEN-LABELED PYRIDO[1,2-A]BENZIMIDAZOLE DERIVATIVE COMPOUND | UNIV KYOTO (JP) | 2020-04-29 | — | — | EP | disclosed |
| US-10081630-B2 | Radioactive halogen-labeled pyrido [1,2-A] benzimidazole derivative compound | KYOTO UNIVERSITY (JP) | 2018-09-25 | — | — | US | disclosed |
| EP-3339309-A1 | RADIOACTIVE HALOGEN-LABELED PYRIDO[1,2-A]BENZIMIDAZOLE DERIVATIVE COMPOUND | Kyoto University (JP) | 2018-06-27 | — | — | EP | disclosed |
| US-20170362226-A1 | RADIOACTIVE HALOGEN-LABELED PYRIDO [1,2-A] BENZIMIDAZOLE DERIVATIVE COMPOUND | KYOTO UNIVERSITY (JP) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10081630-B2 | Radioactive halogen-labeled pyrido [1,2-A] benzimidazole derivative compound | BRI3BP, BRD1, BRDT | APP 4779/4885RAD51 1381/4885TLR9 4780/4885 |
| US-20170362226-A1 | RADIOACTIVE HALOGEN-LABELED PYRIDO [1,2-A] BENZIMIDAZOLE DERIVATIVE COMPOUND | BRI3BP, BRD1, BRDT | APP 4779/4885RAD51 1381/4885TLR9 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.