Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 3/20 | 0.49 |
| ▸ | CHKA | P35790 | 17/20 | 0.48 |
| ▸ | CHKB | Q9Y259 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19813953 | 0.94 | CHKA (0.52) | CHKACHKB | |
| SCHEMBL19813950 | 0.94 | CHKA (0.52) | CHKACHKB | |
| SCHEMBL19714849 | 0.87 | ADCY5 (0.67) | ADCY5CHKA | |
| SCHEMBL19714900 | 0.86 | CHKA (0.61) | ADCY5CHKACHKB | |
| SCHEMBL19714862 | 0.86 | ADCY5 (0.54) | ADCY5CHKACHKB | |
| SCHEMBL19715025 | 0.85 | ADCY5 (0.53) | ADCY5CHKACHKB | |
| SCHEMBL19714911 | 0.85 | ADCY5 (0.53) | ADCY5CHKACHKB | |
| SCHEMBL19820686 | 0.83 | CHKA (0.52) | ADCY5CHKACHKB | |
| SCHEMBL19820684 | 0.83 | CHKA (0.52) | ADCY5CHKACHKB | |
| SCHEMBL19815956 | 0.81 | CHKA (0.45) | CHKACHKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10081633-B2 | Adenylyl cyclase inhibitors, pharmaceutical compositions and method of use thereof | VASADE BIOSCIENCES, INC. | 2018-09-25 | — | — | US | disclosed |
| US-20170362235-A1 | ADENYLYL CYCLASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE THEREOF | VASADE BIOSCIENCES, INC. | 2017-12-21 | — | — | US | disclosed |
| US-20170362235-A1 | ADENYLYL CYCLASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE THEREOF | VASADE BIOSCIENCES, INC. | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10081633-B2 | Adenylyl cyclase inhibitors, pharmaceutical compositions and method of use thereof | ADCY1, ADCY2, ADCY5 | ADCY5 3/4885CHKA 1760/4885CHKB 1311/4885 |
| US-20170362235-A1 | ADENYLYL CYCLASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE THEREOF | ADCY1, ADCY2, ADCY5 | ADCY5 3/4885CHKA 1760/4885CHKB 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.