Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583698 | 0.88 | KMT2A (0.47) | PKMKDM4EMAPTLMNAMEN1 | |
| Histidine SCHEMBL28098393 | 0.78 | CYP1A2 (0.49) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL6856397 | 0.78 | NAMPT (0.42) | CYP1A2PKMSLC7A5L3MBTL1ALDH1A1 | |
| Histidine SCHEMBL29086897 | 0.78 | SLC7A5 (0.47) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL15513862 | 0.78 | CYP1A2 (0.32) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL15755537 | 0.77 | GSK3B (0.45) | CYP1A2LMNAMEN1KMT2AL3MBTL1 | |
| Histidine SCHEMBL16166274 | 0.77 | SLC7A5 (0.47) | CYP1A2ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL1007041 | 0.77 | SLC7A5 (0.63) | CYP1A2ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL638657 | 0.77 | SLC7A5 (0.63) | CYP1A2ALPIPKMPTGS1XIAP | |
| Histidine SCHEMBL28042776 | 0.77 | SLC7A5 (0.47) | CYP1A2ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177530-B1 | Octapeptide having antiangiogenic activity | ABBOTT LAB (US) | 2011-06-22 | — | — | EP | disclosed |
| EP-2177530-A1 | Octapeptide having antiangiogenic activity | Abbott Laboratories (US) | 2010-04-21 | — | — | EP | disclosed |
| US-20080071062-A1 | TETRA-, PENTA-, HEXA- AND HEPTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | HAVIV FORTUNA | 2008-03-20 | — | — | US | disclosed |
| US-20070167376-A1 | Hexa-, Hepta-, and Octapeptides Having Antiangiogenic Activity | HAVIV FORTUNA | 2007-07-19 | — | — | US | disclosed |
| US-7169888-B2 | Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2007-01-30 | — | — | US | disclosed |
| US-7122625-B2 | Hexa-, hepta-, and octapeptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2006-10-17 | — | — | US | disclosed |
| US-20060194737-A1 | Hepta-, octa-and nonapeptides having antiangiogenic activity | HAVIV FORTUNA | 2006-08-31 | — | — | US | disclosed |
| US-7067490-B2 | Hepta-, Octa-and nonapeptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2006-06-27 | — | — | US | disclosed |
| US-7001984-B2 | Di-, tri-, and tetra-peptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2006-02-21 | — | — | US | disclosed |
| EP-1232183-B1 | PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LAB (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20050215484-A1 | Di-, tri-, and tetra-peptides having antiangiogenic activity | HAVIV FORTUNA | 2005-09-29 | — | — | US | disclosed |
| US-6753408-B1 | DRUGS USED FOR THERAPY | ABBVIE INC. | 2004-06-22 | — | — | US | disclosed |