Dl-Phenylalanine

Dl-Phenylalanine

SCHEMBL1007041

NC(Cc1c[nH]cn1)C(=O)O.NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.63
ALPI P09923 1/20 0.63
PKM P14618 1/20 0.63
PTGS1 P23219 1/20 0.63
XIAP P98170 1/20 0.63
SLC1A3 P43003 2/20 0.48
SLC1A2 P43004 2/20 0.48
SLC1A1 P43005 2/20 0.48
GRIA2 P42262 1/20 0.46
CYP1A2 P05177 1/20 0.46
SLC15A1 P46059 1/20 0.44
HSD17B10 Q99714 1/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MPO P05164 1/20 0.43
MAPT P10636 1/20 0.43
TSHR P16473 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL638657 1.00 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28558704 0.95 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8904329 0.95 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28912532 0.95 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL25286397 0.94 SLC7A5 (0.60) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL26918992 0.94 SLC7A5 (0.55) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28504393 0.91 SLC7A5 (0.52) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL14631617 0.91 SLC7A5 (0.52) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28894081 0.91 SLC7A5 (0.52) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL7686784 0.91 SLC7A5 (0.52) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9421190-B2 Compositions comprising amino acids for prevention and/or treatment of renal disorders DETERMINANTS OF METABOLISM RESEARCH LABORATORY S.R.L. (IT) 2016-08-23 US claimed
EP-1888069-B1 ANTIPROLIFERATIVE DRUG EURAND PHARMACEUTICALS LTD (IE) 2009-12-02 EP claimed
US-20080200428-A1 Antiproliferative Drug APTALIS PHARMA LIMITED (IE) 2008-08-21 US claimed
CN-101227906-A Antiproliferative drug EURAND PHARMACEUTICALS LTD (IE) 2008-07-23 CN claimed
EP-1888069-A2 NEW ANTIPROLIFERATIVE DRUG Eurand Pharmaceuticals Ltd (IE) 2008-02-20 EP claimed
WO-2006122954-A2 ANTIPROLIFERATIVE CONJUGATES COMPRISING HYALURONIC ACID AND N-DERIVATIVES OF GLUTAMIC ACID EURAND PHARMACEUTICALS LIMITED (IE) 2006-11-23 WO claimed
US-20050244939-A1 Variant aldolase and processes for producing an optically active IHOG and an optically active monatin using the same AJINOMOTO CO., INC. (JP) 2005-11-03 US claimed
US-20030187049-A1 Compositions based on aminoacids, suitable for improving muscle performance PROFESSIONAL DIETETICS SRL (IT) 2003-10-02 US claimed
CN-115785952-B Light-sensitive peptide element for fluorescent sensing material, preparation method of light-sensitive peptide element, fluorescent sensing material, preparation method of fluorescent sensing material and application of fluorescent sensing material 北京工商大学 2023-08-18 CN disclosed
CN-115785952-A Photosensitive peptide element for fluorescent sensing material and preparation method thereof, fluorescent sensing material and preparation method and application thereof 北京工商大学 2023-03-14 CN disclosed
CN-113424897-A Eucommia ulmoides leaf fermented feed and preparation method thereof 贵州大学 2021-09-24 CN disclosed
US-11060079-B2 Methods and microorganisms for producing flavors and fragrance chemicals ARDRA INC. (CA) 2021-07-13 US disclosed
CN-111406862-A Herbal composition, beverage and preparation method thereof 叶兴良 2020-07-14 CN disclosed
CN-105491982-B Peptides for Enhanced Transdermal Delivery 3M创新有限公司 2019-09-10 CN disclosed
EP-1543122-A2 BITTER TASTE RECEPTORS Deutsches Institut für Ernährungsforschung (DE) 2005-06-22 EP disclosed
WO-2004029087-A2 BITTER TASTE RECEPTORS Deutsches Institut für Ernährungsforschung (DE) 2004-04-08 WO disclosed
CN-1487943-A Process for preparing clopidogrel 2004-04-07 CN disclosed
WO-1996023421-A1 AMINO ACID COMPOSITIONS THE MINISTER OF AGRICULTURE FISHERIES & FOOD IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN & NORTHERN IRELAND (GB) 1996-08-08 WO disclosed
US-5141870-A Transforming plants with mutant fragment confers herbicide resistance E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-25 US disclosed
US-4818700-A Pichia pastoris argininosuccinate lyase gene and uses thereof PHILLIPS PETROLEUM COMPANY (US) 1989-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200428-A1 Antiproliferative Drug CD44, MKI67, HDGF SLC7A5 1176/4885ALPI 842/4885PKM 3987/4885
US-20050244939-A1 Variant aldolase and processes for producing an optically active IHOG and an optically active monatin using the same ALDOA, MON2, HOGA1 SLC7A5 2198/4885ALPI 720/4885PKM 636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.