Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27814440 | 0.84 | NPC1 (0.47) | MAPTALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL26375 | 0.83 | GAA (0.62) | GAAMAPTSRD5A2BCL9CTNNB1 | |
| SCHEMBL28106267 | 0.82 | POLB (0.57) | GAAMAPTSRD5A2ALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL30468845 | 0.81 | GAA (0.61) | GAAMAPTSRD5A2BCL9CTNNB1 | |
| Hydrochloric Acid SCHEMBL7895039 | 0.81 | GAA (0.61) | GAAMAPTSRD5A2BCL9CTNNB1 | |
| Bicarbonate SCHEMBL7985678 | 0.81 | GAA (0.61) | GAAMAPTSRD5A2BCL9CTNNB1 | |
| Pyrazole SCHEMBL21806516 | 0.80 | ALDH1A1 (0.50) | GAAMAPTSRD5A2BCL9CTNNB1 | |
| Nitrobenzene SCHEMBL1628920 | 0.80 | ALDH1A1 (0.57) | MAPTALDH1A1SMN1; SMN2KMT2AL3MBTL1 | |
| Bicarbonate SCHEMBL9330234 | 0.78 | GAA (0.57) | GAAMAPTSRD5A2BCL9CTNNB1 | |
| Cyclohexane SCHEMBL30739999 | 0.78 | GAA (0.57) | GAAMAPTSRD5A2BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986553-B1 | CYCLOBUTYL CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20260068185-A1 | RADIOLIGANDS FOR IMAGING THE LPA1 RECEPTOR | BRISTOL MYERS SQUIBB CO (US) | 2026-03-05 | — | — | US | disclosed |
| US-12466804-B2 | Cyclobutyl carboxylic acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-11-11 | — | — | US | disclosed |
| EP-3986551-B1 | TRIAZOLE CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2025-10-29 | — | — | EP | disclosed |
| US-12435057-B2 | Triazole carboxylic acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-10-07 | — | — | US | disclosed |
| US-12428430-B2 | Oxabicyclo acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-09-30 | — | — | US | disclosed |
| EP-3866692-B1 | RADIOLIGANDS FOR IMAGING THE LPA1 RECEPTOR | BRISTOL MYERS SQUIBB CO (US) | 2025-07-23 | — | — | EP | disclosed |
| US-20250057995-A1 | RADIOLIGANDS FOR IMAGING THE LPA1 RECEPTOR | BRISTOL MYERS SQUIBB CO (US) | 2025-02-20 | — | — | US | disclosed |
| US-20250057815-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2025-02-20 | — | — | US | disclosed |
| US-12209072-B2 | Cyclopentyl acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-01-28 | — | — | US | disclosed |
| WO-2020060915-A1 | CYCLOPENTYL ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020060914-A1 | OXABICYCLO ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020060916-A1 | CYCLOHEPTYL ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-03-26 | — | — | WO | disclosed |
| EP-3472148-B1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2020-03-11 | — | — | EP | disclosed |
| US-10576062-B2 | Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-03-03 | — | — | US | disclosed |
| EP-3472148-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2019-04-24 | — | — | EP | disclosed |
| US-20180333395-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | CHENG PETER TAI WAH (US) | 2018-11-22 | — | — | US | disclosed |
| US-10071078-B2 | Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-09-11 | — | — | US | disclosed |
| WO-2017223016-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-28 | — | — | WO | disclosed |
| US-20170360759-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | SYNGENE INTERNATIONAL LIMITED (IN) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360759-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | LPAR3, LPAR1, LPAR2 | GAA 2004/4885MAPT 1956/4885SRD5A2 3515/4885 |
| US-20250057995-A1 | RADIOLIGANDS FOR IMAGING THE LPA1 RECEPTOR | LPAR1, LPAR3, LPAR2 | GAA 2490/4885MAPT 4082/4885SRD5A2 2647/4885 |
| US-12209072-B2 | Cyclopentyl acids as LPA antagonists | LPAR1, LPAR5, LPAR2 | GAA 2902/4885MAPT 959/4885SRD5A2 1469/4885 |
| US-12435057-B2 | Triazole carboxylic acids as LPA antagonists | LPAR3, LPAR1, LPAR5 | GAA 1901/4885MAPT 632/4885SRD5A2 2425/4885 |
| US-12428430-B2 | Oxabicyclo acids as LPA antagonists | LPAR1, LPAR2, LPAR3 | GAA 2051/4885MAPT 924/4885SRD5A2 1871/4885 |
| US-10576062-B2 | Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists | LPAR3, LPAR1, LPAR2 | GAA 2004/4885MAPT 1956/4885SRD5A2 3515/4885 |
| US-20260068185-A1 | RADIOLIGANDS FOR IMAGING THE LPA1 RECEPTOR | LPAR1, LPAR2, LPAR3 | GAA 4386/4885MAPT 3750/4885SRD5A2 2149/4885 |
| US-20250057815-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | LPAR3, LPAR1, LPAR2 | GAA 2004/4885MAPT 1956/4885SRD5A2 3515/4885 |
| US-12466804-B2 | Cyclobutyl carboxylic acids as LPA antagonists | LPAR1, LPAR3, LPAR2 | GAA 2319/4885MAPT 626/4885SRD5A2 2451/4885 |
| US-20180333395-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | LPAR3, LPAR1, LPAR2 | GAA 2004/4885MAPT 1956/4885SRD5A2 3515/4885 |
| US-10071078-B2 | Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists | LPAR3, LPAR1, LPAR2 | GAA 2004/4885MAPT 1956/4885SRD5A2 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.