SCHEMBL19718322

SCHEMBL19718322

Cc1cc(C)cc(N2C(=C3N(c4cc(C)cc(C)c4)C4CCCCC4N3c3cc(C)ccc3C)N(c3cc(C)cc(C)c3)C3CCCCC32)c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.45
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
USP2 O75604 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 2/20 0.32
GAA P10253 2/20 0.32
FFAR4 Q5NUL3 1/20 0.32
POLB P06746 1/20 0.32
MPI P34949 1/20 0.32
PHOSPHO1 Q8TCT1 1/20 0.32
ALOX12 P18054 1/20 0.32
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16789234 0.83 NR1I2 (0.37) ALDH1A1KMT2ASMN1; SMN2MAPTKDM4E
SCHEMBL20071756 0.77 KMT2A (0.40) SLC18A3TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL16789241 0.75 ALDH1A1 (0.37) SLC18A3ALDH1A1TSHRMEN1KMT2A
SCHEMBL16789227 0.74 CCR1 (0.47) KMT2ASMN1; SMN2LMNAL3MBTL1
SCHEMBL18911719 0.73 HSD17B10 (0.39) SLC18A3HSD17B10ALDH1A1TSHRMEN1
SCHEMBL20071950 0.73 HSD17B10 (0.39) SLC18A3HSD17B10ALDH1A1TSHRMEN1
SCHEMBL16789237 0.73 GAA (0.47) SLC18A3MEN1KMT2AMAPTGAA
SCHEMBL18911718 0.72 HSD17B10 (0.38) SLC18A3HSD17B10ALDH1A1TSHRMEN1
SCHEMBL16789238 0.70 SLC18A3 (0.43) SLC18A3ALDH1A1TSHRMEN1KMT2A
SCHEMBL16789232 0.70 SLC18A3 (0.49) SLC18A3ALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-9846385-B2 Organic light emitting element and display device CANON KABUSHIKI KAISHA (JP) 2017-12-19 US disclosed