Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19828501 | 0.87 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL19721687 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL14346006 | 0.77 | MAOB (0.76) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3045340 | 0.75 | MAOB (0.67) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL7511318 | 0.75 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL14580489 | 0.75 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL15892984 | 0.75 | MAOB (1.00) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL15058644 | 0.74 | MAOB (0.73) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL76133 | 0.74 | MAOB (0.75) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL10047718 | 0.74 | MAOB (0.68) | KDM4EALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3276349-B1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MED SYST INC (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-3029461-B1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MED SYST INC (US) | 2017-12-20 | — | — | EP | disclosed |