Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.73 |
| ▸ | MAOB | P27338 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468836 | 0.95 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10MAOBKMT2A | |
| SCHEMBL14346006 | 0.92 | MAOB (0.76) | KDM4EALDH1A1HSD17B10MAOBKMT2A | |
| SCHEMBL15058644 | 0.86 | MAOB (0.73) | KDM4EALDH1A1HSD17B10MAOBKMT2A | |
| SCHEMBL12611193 | 0.86 | AKR1B10 (0.65) | KDM4EALDH1A1HSD17B10MAOBKMT2A | |
| SCHEMBL15892984 | 0.84 | MAOB (1.00) | KDM4EALDH1A1HSD17B10MAOBKMT2A | |
| SCHEMBL31661779 | 0.84 | NPC1 (0.68) | KDM4EALDH1A1HSD17B10MAOBKMT2A | |
| SCHEMBL5655976 | 0.84 | NPC1 (0.68) | KDM4EALDH1A1HSD17B10MAOBKMT2A | |
| SCHEMBL76133 | 0.83 | MAOB (0.75) | KDM4EALDH1A1HSD17B10MAOBKMT2A | |
| SCHEMBL34468932 | 0.82 | NPC1 (1.00) | KDM4EALDH1A1HSD17B10MAOBKMT2A | |
| SCHEMBL25171308 | 0.81 | AKR1B10 (0.73) | KDM4EALDH1A1HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001020995-A9 | COMPOUNDS DIRECTED AGAINST PILUS BIOGENESIS AND ACTIVITY IN PATHOGENIC BACTERIA; METHODS AND COMPOSITIONS FOR SYNTHESIS THEREOF | UNIV WASHINGTON (US) | 2002-11-14 | — | — | WO | disclosed |
| WO-2001020995-A1 | COMPOUNDS DIRECTED AGAINST PILUS BIOGENESIS AND ACTIVITY IN PATHOGENIC BACTERIA; METHODS AND COMPOSITIONS FOR SYNTHESIS THEREOF | WASHINGTON UNIVERSITY (US) | 2001-03-29 | — | — | WO | disclosed |