SCHEMBL19721856

SCHEMBL19721856

C=C(CO)C(=O)OCCCc1ccc(-c2ccc(C3CCC(CCCCC)CC3)cc2)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.41
FFAR4 Q5NUL3 2/20 0.38
CYP3A4 P08684 3/20 0.37
CYP2C9 P11712 3/20 0.37
APP P05067 2/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
SPHK1 Q9NYA1 6/20 0.35
S1PR1 P21453 2/20 0.33
S1PR3 Q99500 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
AGTR1 P30556 1/20 0.33
AGTR2 P50052 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19722280 0.96 RARB (0.37) RARBFFAR4CYP3A4CYP2C9APP
SCHEMBL19722459 0.95 RARB (0.38) RARBFFAR4CYP3A4CYP2C9APP
SCHEMBL19722448 0.95 RARB (0.41) RARBFFAR4CYP3A4CYP2C9APP
SCHEMBL19722159 0.95 RARB (0.41) RARBFFAR4CYP3A4CYP2C9APP
SCHEMBL19722326 0.95 RARB (0.43) RARBFFAR4CYP3A4CYP2C9APP
SCHEMBL19721871 0.93 RARB (0.41) RARBFFAR4CYP3A4CYP2C9APP
SCHEMBL19722393 0.92 RARB (0.45) RARBFFAR4CYP3A4CYP2C9CYP2D6
SCHEMBL19722224 0.91 RARB (0.40) RARBFFAR4CYP3A4CYP2C9APP
SCHEMBL19721844 0.91 RARB (0.40) RARBFFAR4CYP2C9SPHK1S1PR1
SCHEMBL19722199 0.91 FFAR4 (0.38) FFAR4CYP2C9SPHK1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 US disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 RARB 2607/4885FFAR4 2665/4885CYP3A4 2747/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 RARB 1568/4885FFAR4 2555/4885CYP3A4 3484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.