SCHEMBL19721890

SCHEMBL19721890

C=C(CO)C(=O)OCCc1ccc(-c2ccc(-c3ccc(C4CCC(CCCCC)CC4)cc3)c(CC)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 2/20 0.38
▸ SPHK1 Q9NYA1 11/20 0.35
▸ CYP2C9 P11712 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ P2RY14 Q15391 1/20 0.32
▸ DGAT1 O75907 1/20 0.32
▸ SPHK2 Q9NRA0 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19722527 0.96 FFAR4 (0.39) FFAR4SPHK1CYP2C9SPHK2
SCHEMBL19755090 0.96 FFAR4 (0.39) FFAR4SPHK1CYP2C9SPHK2
SCHEMBL19755092 0.94 FFAR4 (0.39) FFAR4SPHK1SPHK2
SCHEMBL20313610 0.94 FFAR4 (0.34) FFAR4SPHK1CYP2C9ALDH1A1LMNA
SCHEMBL19722437 0.91 FFAR4 (0.39) FFAR4SPHK1CYP2C9ALDH1A1LMNA
SCHEMBL19722224 0.91 RARB (0.40) FFAR4SPHK1CYP2C9P2RY14
SCHEMBL19722063 0.91 FFAR4 (0.39) FFAR4CYP2C9P2RY14
SCHEMBL19722199 0.91 FFAR4 (0.38) FFAR4SPHK1CYP2C9ALDH1A1LMNA
SCHEMBL19755072 0.90 CYP2C9 (0.36) FFAR4SPHK1CYP2C9ALDH1A1LMNA
SCHEMBL19855551 0.89 FFAR4 (0.34) FFAR4CYP2C9ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 — — EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 — — US disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 — — US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 FFAR4 2665/4885SPHK1 435/4885CYP2C9 4226/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 FFAR4 2555/4885SPHK1 646/4885CYP2C9 4442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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