Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | RARA | P10276 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | THRA | P10827 | 6/20 | 0.55 |
| ▸ | THRB | P10828 | 6/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21093716 | 0.83 | RARB (0.66) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL10415435 | 0.81 | THRB (0.53) | MEN1KMT2AALDH1A1MAPTTHRA | |
| SCHEMBL10379965 | 0.81 | RARB (0.68) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL31549867 | 0.81 | RARB (0.68) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL28032480 | 0.81 | THRA (0.61) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL20082930 | 0.81 | THRA (0.57) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL19235338 | 0.81 | RARB (0.55) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL11664249 | 0.79 | RARB (0.73) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL11661972 | 0.79 | HSD17B10 (0.71) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL11657350 | 0.79 | HSD17B10 (0.71) | RARBMEN1KMT2AALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257839-A1 | POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2017-12-20 | — | — | EP | disclosed |