SCHEMBL19722033

SCHEMBL19722033

C=C(CO)C(=O)OCCOc1ccc(-c2ccc(-c3ccc(CCCCC)cc3)cc2CC)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.46
▸ USP2 O75604 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ CASP1 P29466 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ SLCO1B3 Q9NPD5 1/20 0.46
▸ SLCO1B1 Q9Y6L6 1/20 0.46
▸ PTPN11 Q06124 1/20 0.41
▸ RARB P10826 10/20 0.41
▸ RARA P10276 2/20 0.41
▸ PLA2G4A P47712 1/20 0.41
▸ THRB P10828 1/20 0.40
▸ RARG P13631 1/20 0.39
▸ FFAR4 Q5NUL3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19721938 0.97 PTPN11 (0.43) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL21465939 0.94 PTPN11 (0.45) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL19855548 0.93 MEN1 (0.41) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL20313562 0.93 MEN1 (0.41) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL20313564 0.92 MEN1 (0.42) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL19755077 0.92 RARB (0.43) MEN1ALDH1A1KMT2ARARBRARA
SCHEMBL19722157 0.92 RARB (0.43) MEN1ALDH1A1KMT2ARARBRARA
SCHEMBL19722273 0.92 RARB (0.43) MEN1ALDH1A1KMT2ARARBRARA
SCHEMBL19854384 0.91 RARB (0.44) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL19855276 0.91 RARB (0.44) MEN1USP2ALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 — — EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 — — US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 MEN1 90/4885USP2 3703/4885ALDH1A1 3882/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 MEN1 195/4885USP2 3567/4885ALDH1A1 3267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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