SCHEMBL19722040

SCHEMBL19722040

C=C(CCN(C)CC)C(=O)Oc1ccc(-c2ccc(CCCCC)cc2F)cc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 4/20 0.47
▸ THRB P10828 6/20 0.40
▸ FAAH O00519 1/20 0.39
▸ PTGS2 P35354 1/20 0.39
▸ THRA P10827 5/20 0.39
▸ RARA P10276 1/20 0.38
▸ RARG P13631 1/20 0.38
▸ S1PR1 P21453 3/20 0.36
▸ S1PR3 Q99500 2/20 0.36
▸ MAPT P10636 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19722473 0.92 RARB (0.48) RARBTHRBFAAHPTGS2THRA
SCHEMBL19722103 0.88 RARB (0.52) RARBTHRBFAAHPTGS2THRA
SCHEMBL19721973 0.87 RARB (0.51) RARBTHRBFAAHPTGS2THRA
SCHEMBL19721983 0.86 RARB (0.54) RARBTHRBFAAHPTGS2THRA
SCHEMBL19722548 0.84 RARB (0.52) RARBTHRBFAAHPTGS2THRA
SCHEMBL19721816 0.83 RARB (0.54) RARBTHRBFAAHPTGS2THRA
SCHEMBL19721838 0.83 RARB (0.51) RARBTHRBFAAHPTGS2THRA
SCHEMBL23635420 0.83 RARB (0.58) RARBTHRBFAAHPTGS2THRA
SCHEMBL15385623 0.83 RARB (0.55) RARBTHRBFAAHPTGS2THRA
SCHEMBL19722533 0.82 RARB (0.53) RARBTHRBTHRARARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 — — EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 — — US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 RARB 2607/4885THRB 4606/4885FAAH 3729/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 RARB 1568/4885THRB 4233/4885FAAH 3821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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