SCHEMBL19722083

SCHEMBL19722083

C=C(CO)C(=O)Oc1ccc(-c2ccc(C3CCC(CCCF)CC3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.36
DGAT1 O75907 8/20 0.35
CYP2C9 P11712 2/20 0.35
SOAT1 P35610 3/20 0.35
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
FFAR4 Q5NUL3 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ESR1 P03372 1/20 0.33
CYP3A4 P08684 1/20 0.33
ESRRG P62508 1/20 0.32
LSS P48449 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19855427 0.89 ESR2 (0.34) ESR2DGAT1CYP2C9SOAT1ALDH1A1
SCHEMBL19721990 0.88 CYP2C9 (0.42) ESR2DGAT1CYP2C9SOAT1ALDH1A1
SCHEMBL19722377 0.87 CYP2C9 (0.41) ESR2DGAT1CYP2C9SOAT1ALDH1A1
SCHEMBL19722118 0.87 CYP2C9 (0.41) ESR2DGAT1CYP2C9SOAT1ALDH1A1
SCHEMBL19721907 0.84 ESR2 (0.39) ESR2DGAT1CYP2C9ALDH1A1LMNA
SCHEMBL19721958 0.84 FFAR4 (0.38) ESR2DGAT1CYP2C9SOAT1ALDH1A1
SCHEMBL19721839 0.84 CYP2C9 (0.44) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL19722188 0.83 CYP2C9 (0.43) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL19722254 0.83 CYP2C9 (0.43) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL19722277 0.82 CYP2C9 (0.53) ESR2DGAT1CYP2C9SOAT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 WO disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 ESR2 2127/4885DGAT1 4507/4885CYP2C9 4226/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 ESR2 2096/4885DGAT1 4598/4885CYP2C9 4442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.