SCHEMBL19722387

SCHEMBL19722387

C=C(CO)C(=O)OC1CCC(c2ccc(-c3ccc(C4CCC(CCCCC)CC4)cc3F)cc2F)CC1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 1/20 0.36
▸ CYP2C9 P11712 3/20 0.34
▸ CYP3A4 P08684 3/20 0.34
▸ FASN P49327 1/20 0.34
▸ OPRL1 P41146 8/20 0.33
▸ APP P05067 2/20 0.33
▸ DGAT1 O75907 1/20 0.32
▸ RARB P10826 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ NAAA Q02083 1/20 0.31
▸ GPR119 Q8TDV5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19722219 0.93 CYP2C9 (0.39) FFAR4CYP2C9CYP3A4FASNAPP
SCHEMBL19722416 0.93 CYP2C9 (0.39) FFAR4CYP2C9CYP3A4FASNAPP
SCHEMBL19722400 0.91 OPRL1 (0.35) CYP2C9OPRL1NAAAGPR119
SCHEMBL19721850 0.91 OPRL1 (0.35) CYP2C9OPRL1NAAAGPR119
SCHEMBL19722078 0.91 OPRL1 (0.35) CYP2C9OPRL1NAAAGPR119
SCHEMBL19722372 0.91 OPRL1 (0.35) CYP2C9OPRL1NAAAGPR119
SCHEMBL19855435 0.87 FFAR4 (0.32) FFAR4CYP2C9CYP3A4FASNAPP
SCHEMBL19721869 0.85 CYP2C9 (0.37) FFAR4CYP2C9CYP3A4FASNAPP
SCHEMBL20882880 0.84 FFAR4 (0.31) FFAR4CYP2C9CYP3A4FASNAPP
SCHEMBL19855729 0.84 FASN (0.32) FFAR4CYP2C9CYP3A4FASNAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 — — EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 — — US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 FFAR4 2665/4885CYP2C9 4226/4885CYP3A4 2747/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 FFAR4 2555/4885CYP2C9 4442/4885CYP3A4 3484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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