Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30074087 | 1.00 | ATM (0.53) | ATMTDP1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3401772 | 0.87 | TDP1 (0.52) | ATMTDP1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL30800770 | 0.85 | TDP1 (0.58) | ATMTDP1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL525939 | 0.85 | TDP1 (0.58) | ATMTDP1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL23648164 | 0.81 | TDP1 (0.53) | ATMTDP1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6520096 | 0.81 | TDP1 (0.53) | ATMTDP1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL20560688 | 0.81 | ALDH1A1 (0.56) | ATMTDP1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL194408 | 0.81 | ATM (0.53) | ATMTDP1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL14713516 | 0.81 | TDP1 (0.52) | TDP1ALDH1A1L3MBTL1MAPTMAPK1 | |
| SCHEMBL10019199 | 0.81 | TDP1 (0.49) | ATMTDP1ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400166-A2 | METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | Contraline, Inc. (US) | 2024-07-17 | — | — | EP | claimed |
| EP-3565484-B1 | COMPOSITIONS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | CONTRALINE INC (US) | 2024-04-03 | — | — | EP | claimed |
| CN-117700368-A | Synthesis method of pentanitrogen guanidine salt chiral phase transfer catalyst | 四川大学 | 2024-03-15 | — | — | CN | claimed |
| EP-3565484-A1 | METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | Contraline, Inc. (US) | 2019-11-13 | — | — | EP | claimed |
| WO-2018129369-A1 | METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | Contraline, Inc. (US) | 2018-07-12 | — | — | WO | claimed |
| US-20180185096-A1 | METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | Contraline, Inc. | 2018-07-05 | — | — | US | claimed |
| US-12383421-B2 | Contraceptive devices | Contraline, Inc. (US) | 2025-08-12 | — | — | US | disclosed |
| CN-118530224-A | Pyrimidinone compound and application thereof | 深圳安泰维生物医药有限公司 | 2024-08-23 | — | — | CN | disclosed |
| EP-4400166-A2 | METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | Contraline, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| EP-3565484-B1 | COMPOSITIONS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | CONTRALINE INC (US) | 2024-04-03 | — | — | EP | disclosed |
| CN-117700368-A | Synthesis method of pentanitrogen guanidine salt chiral phase transfer catalyst | 四川大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-109983014-B | Mutant isocitrate dehydrogenase inhibitors, compositions and methods thereof | 艾科生物科技有限公司 | 2022-12-23 | — | — | CN | disclosed |
| US-20210101899-A1 | INHIBITORS OF MUTANT ISOCITRATE DEHYDROGENASES AND COMPOSITIONS AND METHODS THEREOF | ISOCURE BIOSCIENCES INC (US) | 2021-04-08 | — | — | US | disclosed |
| EP-0549666-A1 | NOVEL AMINOBENZOSULTAM DERIVATIVES AS LIPOXYGENASE INHIBITORS. | PFIZER (US) | 1993-07-07 | — | — | EP | disclosed |
| WO-1992005164-A1 | NOVEL AMINOBENZOSULTAM DERIVATIVES AS LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1992-04-02 | — | — | WO | disclosed |
| US-4486355-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-04 | — | — | US | disclosed |
| US-4385070-A | CYCLOPROPANE DERIVATIVES AS INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-24 | — | — | US | disclosed |
| EP-0016513-B1 | ESTERS OF HALOGENATED SUBSTITUTED CYCLOPROPANOIC ACIDS, THEIR PREPARATION AND USE AS INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-23 | — | — | EP | disclosed |
| EP-0032121-A2 | Substituted tetrafluorobenzyl alcohols and halides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-15 | — | — | EP | disclosed |
| EP-0016513-A2 | Esters of halogenated substituted cyclopropanoic acids, their preparation and use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101899-A1 | INHIBITORS OF MUTANT ISOCITRATE DEHYDROGENASES AND COMPOSITIONS AND METHODS THEREOF | IDH1, IDH2, IDH3A | ATM 423/4885TDP1 192/4885ALDH1A1 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.