Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23009237 | 0.78 | KDM4E (0.59) | ALDH1A1APPKDM4EPOLBHSD17B10 | |
| SCHEMBL15502284 | 0.76 | NPC1 (0.51) | ALDH1A1APPKDM4EPOLBHSD17B10 | |
| SCHEMBL2020170 | 0.75 | KDM4E (0.54) | ALDH1A1KDM4EPOLBHSD17B10LMNA | |
| SCHEMBL2024081 | 0.75 | KDM4E (0.54) | ALDH1A1KDM4EPOLBHSD17B10LMNA | |
| SCHEMBL1876646 | 0.73 | ADORA2A (0.51) | ALDH1A1APPKDM4EBCHEACHE | |
| SCHEMBL28910000 | 0.72 | POLB (0.61) | ALDH1A1KDM4EPOLBHSD17B10LMNA | |
| SCHEMBL28026104 | 0.72 | POLB (0.59) | ALDH1A1KDM4EPOLBHSD17B10LMNA | |
| SCHEMBL27787446 | 0.72 | DCPS (0.57) | ALDH1A1APPKDM4EPOLBHSD17B10 | |
| SCHEMBL12637539 | 0.71 | TRIM24 (0.54) | ALDH1A1KDM4EPOLBHSD17B10LMNA | |
| SCHEMBL12637535 | 0.71 | TRIM24 (0.54) | ALDH1A1KDM4EPOLBHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709989-B1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES | JANSSEN SCIENCES IRELAND UC (IE) | 2017-12-20 | — | — | EP | disclosed |