Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21964140 | 0.86 | MPO (0.60) | KDM4EHTTHPGDALDH1A1KMT2A | |
| SCHEMBL12501235 | 0.82 | KDM4E (0.58) | KDM4EHTTHPGDALDH1A1KMT2A | |
| SCHEMBL15502284 | 0.81 | NPC1 (0.51) | KDM4EHTTHPGDALDH1A1HSD17B10 | |
| SCHEMBL12501234 | 0.79 | KDM4E (0.55) | KDM4EHTTHPGDALDH1A1KMT2A | |
| SCHEMBL29538580 | 0.79 | KDM4E (0.59) | KDM4EHTTHPGDALDH1A1KMT2A | |
| SCHEMBL2534998 | 0.79 | KDM4E (0.55) | KDM4EHTTHPGDALDH1A1KMT2A | |
| SCHEMBL620402 | 0.79 | KDM4E (0.56) | KDM4EHTTHPGDALDH1A1KMT2A | |
| SCHEMBL15450912 | 0.78 | ALDH1A1 (0.60) | KDM4EHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL19723014 | 0.78 | ALDH1A1 (0.46) | KDM4EHTTHPGDALDH1A1HSD17B10 | |
| SCHEMBL1876646 | 0.78 | ADORA2A (0.51) | KDM4EHTTALDH1A1NQO2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210045387-A1 | COMPOSITIONS AND METHODS TO INHIBIT ARTHROPOD HOST-SEEKING BEHAVIOR | THE ROCKEFELLER UNIVERSITY (US) | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210045387-A1 | COMPOSITIONS AND METHODS TO INHIBIT ARTHROPOD HOST-SEEKING BEHAVIOR | CHIA, CFH, C5 | KDM4E 3506/4885HTT 1646/4885HPGD 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.