Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | STAT3 | P40763 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bisabolol Acetate SCHEMBL4279285 | 0.85 | LMNA (1.00) | LMNACYP3A4ALOX15STAT3MEN1 | |
| SCHEMBL13136691 | 0.77 | ALOX15 (0.74) | LMNACYP3A4ALOX15STAT3MEN1 | |
| SCHEMBL3053446 | 0.77 | ALOX15 (0.74) | LMNACYP3A4ALOX15STAT3MEN1 | |
| Dimethylamine SCHEMBL4978247 | 0.76 | CYP3A4 (0.73) | LMNACYP3A4ALOX15STAT3MEN1 | |
| SCHEMBL13177710 | 0.75 | ALOX15 (0.72) | LMNACYP3A4ALOX15STAT3MEN1 | |
| SCHEMBL8510625 | 0.74 | LMNA (0.70) | LMNACYP3A4ALOX15STAT3MEN1 | |
| Linalyl Acetate SCHEMBL28096246 | 0.73 | ALOX15 (0.68) | LMNACYP3A4ALOX15STAT3MEN1 | |
| SCHEMBL63131 | 0.72 | CYP3A4 (0.67) | LMNACYP3A4ALOX15STAT3MEN1 | |
| Levomenol SCHEMBL14515491 | 0.71 | ALOX15 (1.00) | LMNACYP3A4ALOX15STAT3MEN1 | |
| Levomenol SCHEMBL1245143 | 0.71 | ALOX15 (1.00) | LMNACYP3A4ALOX15STAT3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648689-B1 | 2-PYRONES | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |