Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19723613 | 0.91 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAKMT2AHTTKDM4E | |
| SCHEMBL12294580 | 0.89 | ALDH1A1 (0.60) | SMN1; SMN2LMNAKMT2AHTTKDM4E | |
| SCHEMBL19723614 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAKMT2AHTTKDM4E | |
| SCHEMBL19723738 | 0.86 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNAKMT2AHTTKDM4E | |
| SCHEMBL12295298 | 0.82 | LMNA (0.54) | SMN1; SMN2LMNAKMT2ARAB9AHTT | |
| SCHEMBL17876464 | 0.81 | CYP2C9 (0.61) | SMN1; SMN2LMNAKMT2ARAB9AGALR3 | |
| SCHEMBL19723805 | 0.80 | MAPK14 (0.53) | SMN1; SMN2LMNAHTTKDM4EPKM | |
| SCHEMBL19723642 | 0.79 | MAPT (0.57) | SMN1; SMN2LMNAKMT2AHTTKDM4E | |
| SCHEMBL19723643 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2KMT2ARAB9AKDM4ETHRB | |
| SCHEMBL12294855 | 0.79 | KDM4E (0.55) | SMN1; SMN2LMNAKMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257854-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | University of Notre Dame du Lac (US) | 2017-12-20 | — | — | EP | disclosed |