Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.49 |
| ▸ | BCHE | P06276 | 11/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19122026 | 1.00 | ACHE (0.49) | ACHEBCHEFAAHAOC3ACP3 | |
| SCHEMBL16363245 | 1.00 | ACHE (0.49) | ACHEBCHEFAAHAOC3ACP3 | |
| SCHEMBL24222513 | 0.80 | ACHE (0.50) | ACHEBCHEFAAHMARK4MEN1 | |
| SCHEMBL12244188 | 0.77 | ACP3 (0.42) | ACHEBCHEFAAHAOC3ACP3 | |
| SCHEMBL10076821 | 0.77 | ACHE (0.45) | ACHEBCHEFAAHAOC3ACP3 | |
| SCHEMBL15131157 | 0.77 | HRH1 (0.51) | AOC3ACP3MAPT | |
| SCHEMBL8470837 | 0.77 | ACHE (0.50) | ACHEAOC3ACP3ALDH1A1MAPK1 | |
| SCHEMBL5913712 | 0.77 | ACHE (0.47) | ACHEBCHEFAAHMARK4MEN1 | |
| SCHEMBL21128963 | 0.77 | ACHE (0.47) | ACHEBCHEFAAHAOC3ACP3 | |
| SCHEMBL12557215 | 0.77 | ADRB1 (0.53) | ACHEBCHEFAAHMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242207-A1 | KRAS INHIBITORS FOR TREATMENT OF CANCERS | Tyligand Bioscience (Shanghai) Limited (CN) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022095960-A1 | KRAS INHIBITORS FOR TREATMENT OF CANCERS | 泰励生物科技（上海）有限公司 | 2022-05-12 | — | — | WO | disclosed |
| EP-3594202-B1 | SUBSTITUTED PYRROLIDINE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-08-11 | — | — | EP | disclosed |
| EP-2582799-B1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (S)-3-(1-AMINOETHYL)-PHENOL | CODEXIS INC (US) | 2017-12-20 | — | — | EP | disclosed |