SCHEMBL1972587

SCHEMBL1972587

C=CC(=O)OCCc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 5/20 0.51
THRB P10828 1/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
USP2 O75604 1/20 0.48
GAA P10253 1/20 0.48
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
HPGD P15428 4/20 0.46
MAPK1 P28482 3/20 0.46
LMNA P02545 3/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 2/20 0.46
SLC6A2 P23975 2/20 0.46
CYP2C19 P33261 2/20 0.46
PGR P06401 1/20 0.46
PDE4A P27815 1/20 0.46
HRH1 P35367 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23196587 0.93 THRB (0.46) APPTHRBMEN1KMT2AUSP2
SCHEMBL64457 0.84 THRB (0.60) THRBMEN1KMT2AUSP2GAA
SCHEMBL29396444 0.84 THRB (0.60) THRBMEN1KMT2AUSP2GAA
SCHEMBL27890949 0.83 THRB (0.56) APPTHRBMEN1KMT2AGAA
Acrylic Acid SCHEMBL28094490 0.82 THRB (0.58) THRBMEN1KMT2AUSP2GAA
SCHEMBL29985941 0.81 HPGD (0.48) APPMEN1KMT2AUSP2GAA
SCHEMBL1823463 0.81 HPGD (0.48) APPMEN1KMT2AUSP2GAA
SCHEMBL23839109 0.81 GAA (0.44) APPTHRBMEN1KMT2AUSP2
SCHEMBL16693326 0.81 APP (0.42) APPTHRBMEN1KMT2AHPGD
SCHEMBL30234328 0.81 HPGD (0.56) THRBMEN1KMT2AUSP2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433327-A Artificial crystal material and preparation method and application thereof 四川兴泰普乐医疗科技有限公司 2022-12-06 CN disclosed
EP-3124525-B1 POLYMER SUBSTRATE WITH HARD COAT LAYER AND MANUFACTURING METHOD FOR SUCH POLYMER SUBSTRATE TEIJIN LTD (JP) 2020-11-04 EP disclosed
EP-2747921-B1 ORGANIC RESIN LAMINATE, METHODS OF MAKING AND USING THE SAME, AND ARTICLES COMPRISING THE SAME EXATEC LLC (US) 2017-11-01 EP disclosed
US-9758630-B2 Polymer substrate with hard coat layer and manufacturing method for such polymer substrate TEIJIN LIMITED (JP) 2017-09-12 US disclosed
US-20170107345-A1 POLYMER SUBSTRATE WITH HARD COAT LAYER AND MANUFACTURING METHOD FOR SUCH POLYMER SUBSTRATE TEIJIN LIMITED (JP) 2017-04-20 US disclosed
EP-2868717-B1 Titania-containing coating composition and coated article SHINETSU CHEMICAL CO (JP) 2017-04-19 EP disclosed
EP-2508579-B1 Weather-Resistant Hard Coating Composition and Coated Article SHINETSU CHEMICAL CO (JP) 2017-04-19 EP disclosed
EP-3124525-A1 POLYMER SUBSTRATE WITH HARD COAT LAYER AND MANUFACTURING METHOD FOR SUCH POLYMER SUBSTRATE Teijin Limited (JP) 2017-02-01 EP disclosed
US-9441133-B2 Organic resin laminate, methods of making and using the same, and articles comprising the same EXATEC, LLC (US) 2016-09-13 US disclosed
EP-1995056-B1 MULTILAYER BODY TEIJIN CHEMICALS LTD (JP) 2016-08-17 EP disclosed
US-20040247878-A1 Acrylic resin composition organosiloxane resin composition and laminate comprising the same TEIJIN CHEMICALS LTD. (JP) 2004-12-09 US disclosed
EP-1122278-B1 Coating composition, coating method, and coated article SHINETSU CHEMICAL CO (JP) 2004-09-22 EP disclosed
EP-1418198-A1 Primer coating composition and coating method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-05-12 EP disclosed
US-20040087711-A1 Coating composition, coating method, and coated article SHIN-ETSU CHEMICAL CO., LTD. 2004-05-06 US disclosed
EP-1408082-A2 Primer composition, coating method, and coated article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-04-14 EP disclosed
US-6677047-B2 BENZOTRIAZOLE COMPOUND HAVING A VINYL GROUP MODIFIED THROUGH ITS HYDROXY GROUP WITH A SILANE COMPOUND; TRANSPARENT COATINGS FOR POLYCARBONATE SUBSTRATES WITH MAR, WEATHER, AND CHEMICAL RESISTANCE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-01-13 US disclosed
US-6497964-B1 MIXTURES OF A SILANE AND A BENZOPHENONE-SILANE CONDENSATE USED APPLIED TO POLYCARBONATES, THEN CURED TO FORM ULTRAVIOLET ABSORBER MATERIALS AND PROTECTIVE COATINGS HAVING WEAR AND WEATHER RESISTANCE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-12-24 US disclosed
US-20010036986-A1 Coating composition, coating method, and coated article KABUSHIKI KAISHA TOYODA JIDOSHOKKI SEISAKUSHO (JP) 2001-11-01 US disclosed
EP-1122278-A2 Coating composition, coating method, and coated article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-08 EP disclosed
EP-1070750-A2 Coating compositions and method for the surface protection of plastic substrate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-01-24 EP disclosed