SCHEMBL64457

SCHEMBL64457

C=CC(=O)OCCOc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.60
HPGD P15428 3/20 0.57
LMNA P02545 4/20 0.54
MAPK1 P28482 2/20 0.54
CYP1A2 P05177 2/20 0.54
PGR P06401 2/20 0.54
SLC6A2 P23975 2/20 0.54
CYP2C19 P33261 2/20 0.54
ALDH1A1 P00352 1/20 0.54
CYP2D6 P10635 1/20 0.54
PDE4A P27815 1/20 0.54
HRH1 P35367 1/20 0.54
HTT P42858 1/20 0.54
SLC6A3 Q01959 1/20 0.54
PDE4D Q08499 1/20 0.54
GAA P10253 2/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
KMT2A Q03164 1/20 0.50
KEAP1 Q14145 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396444 1.00 THRB (0.60) THRBHPGDLMNAMAPK1CYP1A2
Acrylic Acid SCHEMBL28094490 0.98 THRB (0.58) THRBHPGDLMNAMAPK1CYP1A2
SCHEMBL30234328 0.94 HPGD (0.56) THRBHPGDLMNAMAPK1CYP1A2
SCHEMBL4190221 0.94 HPGD (0.56) THRBHPGDLMNAMAPK1CYP1A2
SCHEMBL15820013 0.94 HPGD (0.56) THRBHPGDLMNAMAPK1CYP1A2
Hydrochloric Acid SCHEMBL17114673 0.92 HPGD (0.52) THRBHPGDLMNAMAPK1CYP1A2
SCHEMBL4191413 0.89 THRB (0.58) THRBHPGDLMNAMAPK1CYP1A2
SCHEMBL18049515 0.88 LMNA (0.52) THRBHPGDLMNAMAPK1CYP1A2
SCHEMBL30306614 0.88 THRB (0.51) THRBHPGDLMNAMAPK1CYP1A2
SCHEMBL15820262 0.88 THRB (0.51) THRBHPGDLMNAMAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2743 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577345-B2 Radiation blockers for contact lenses COOPERVISION INTERNATIONAL LIMITED (GB) 2026-03-17 US claimed
US-20260042870-A1 BINDER COMPOSITIONS AND USES THEREOF KNAUF INSULATION SPRL (BE) 2026-02-12 US claimed
US-20260000813-A1 Multifunctional Crosslinkers: Compounds, Compositions, And Products Thereof BIOCOAT INCORPORATED (US) 2026-01-01 US claimed
US-12466899-B2 Binder compositions and uses thereof KNAUF INSULATION SPRL (BE) 2025-11-11 US claimed
EP-4519721-B1 RADIATION BLOCKERS FOR CONTACT LENSES COOPERVISION INT LTD (GB) 2025-10-01 EP claimed
CN-120025694-A Special high-performance modified asphalt for high-speed pavement and preparation method thereof 辽宁步云交通新材料科技有限公司 2025-05-23 CN claimed
CN-120002973-A Preparation process of ultralow-temperature single PP recyclable composite packaging film 安徽紫金新材料科技股份有限公司 2025-05-16 CN claimed
US-12269909-B2 Polymer composition and a method of preparing a polymer resin AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2025-04-08 US claimed
US-20250109234-A1 RADIATION BLOCKERS FOR CONTACT LENSES COOPERVISION INTERNATIONAL LIMITED (GB) 2025-04-03 US claimed
EP-4519721-A1 RADIATION BLOCKERS FOR CONTACT LENSES CooperVision International Limited (GB) 2025-03-12 EP claimed
EP-0431015-A1 MODIFIED POLYMERS 3i RESEARCH EXPLOITATION LIMITED (GB) 1991-06-12 EP claimed
US-5002979-A Hyydrogenorganosilicon monomer, organosilicon, fluoroorgano monomer, a hydrophobic monomer and a crosslinking agent BAUSCH & LOMB INCORPORATED (US) 1991-03-26 US claimed
EP-0211067-B1 OXYGEN-PERMEABLE LENSES Bausch & Lomb Incorporated (US) 1991-03-13 EP claimed
EP-0357267-A1 Modified polymers 3i RESEARCH EXPLOITATION LIMITED (GB) 1990-03-07 EP claimed
WO-1990001506-A1 MODIFIED POLYMERS 3I RESEARCH EXPLOITATION LIMITED (GB) 1990-02-22 WO claimed
EP-0211067-A1 OXYGEN-PERMEABLE LENSES. BAUSCH & LOMB (US) 1987-02-25 EP claimed
EP-0209597-A1 EXTENDED-WEAR LENSES Bausch & Lomb Incorporated (US) 1987-01-28 EP claimed
EP-0209299-A1 Copolymers of ethylene and unsaturated ester MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1987-01-21 EP claimed
WO-1986004342-A1 OXYGEN-PERMEABLE LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO claimed
WO-1986004343-A1 EXTENDED-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO claimed