Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12792111 | 0.99 | KDM4E (0.47) | KDM4EATML3MBTL1NPSR1HDAC4 | |
| SCHEMBL23181659 | 0.99 | KDM4E (0.47) | KDM4EATML3MBTL1NPSR1HDAC4 | |
| SCHEMBL12792050 | 0.99 | KDM4E (0.47) | KDM4EATML3MBTL1NPSR1HDAC4 | |
| SCHEMBL12792080 | 0.97 | KDM4E (0.45) | KDM4EATML3MBTL1NPSR1HDAC4 | |
| SCHEMBL10027641 | 0.89 | L3MBTL1 (0.62) | KDM4EATML3MBTL1HDAC4JAK2 | |
| SCHEMBL10027526 | 0.89 | L3MBTL1 (0.62) | KDM4EATML3MBTL1HDAC4JAK2 | |
| SCHEMBL12691126 | 0.89 | L3MBTL1 (0.62) | KDM4EATML3MBTL1HDAC4JAK2 | |
| SCHEMBL17245455 | 0.89 | L3MBTL1 (0.62) | KDM4EATML3MBTL1HDAC4JAK2 | |
| SCHEMBL31744513 | 0.89 | L3MBTL1 (0.62) | KDM4EATML3MBTL1HDAC4JAK2 | |
| SCHEMBL26060236 | 0.89 | L3MBTL1 (0.62) | KDM4EATML3MBTL1HDAC4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170365789-A1 | COMPOUND, MIXTURE COMPRISING THE SAME, COMPOSITION AND ORGANIC ELECTRONIC DEVICE | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170365789-A1 | COMPOUND, MIXTURE COMPRISING THE SAME, COMPOSITION AND ORGANIC ELECTRONIC DEVICE | DDT, DRD3, ICMT | KDM4E 1611/4885ATM 2127/4885L3MBTL1 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.