Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16691371 | 0.94 | SAT1 (0.53) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL16691373 | 0.92 | SAT1 (0.52) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL19728164 | 0.90 | SAT1 (0.46) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL23059867 | 0.90 | SAT1 (0.46) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL24845617 | 0.88 | SAT1 (0.49) | SAT1GNAI3GNAO1GNAI1CYP1A2 | |
| SCHEMBL4670470 | 0.86 | SAT1 (0.48) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL19734413 | 0.79 | SAT1 (0.42) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL21743264 | 0.78 | ALDH1A1 (0.46) | SAT1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL19728163 | 0.77 | ALDH1A1 (0.44) | SAT1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29827347 | 0.77 | SAT1 (0.53) | SAT1GNAI3GNAO1GNAI1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362217-A1 | Substituted Piperidine Compounds | Epizyme, Inc. (US) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362217-A1 | Substituted Piperidine Compounds | SMYD3, SMYD2, SNRPD3 | SAT1 597/4885GNAI3 405/4885GNAO1 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.