Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670470 | 0.92 | SAT1 (0.48) | SAT1ALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL21743264 | 0.83 | ALDH1A1 (0.46) | SAT1ALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL19728163 | 0.82 | ALDH1A1 (0.44) | SAT1ALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL19728162 | 0.79 | SAT1 (0.55) | SAT1ALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL13766693 | 0.78 | GNAI3 (0.54) | SAT1ALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL12156661 | 0.78 | KMT2A (0.45) | SAT1ALDH1A1CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL16691371 | 0.78 | SAT1 (0.53) | SAT1ALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL24540363 | 0.77 | SAT1 (0.52) | SAT1MEN1KMT2AGNAI3GNAO1 | |
| SCHEMBL16691373 | 0.76 | SAT1 (0.52) | SAT1ALDH1A1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL82228 | 0.75 | SAT1 (0.45) | SAT1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577363-B2 | Substituted piperidine compounds | Epizyme, Inc. (US) | 2020-03-03 | — | — | US | disclosed |
| US-20170362217-A1 | Substituted Piperidine Compounds | Epizyme, Inc. (US) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577363-B2 | Substituted piperidine compounds | SMYD3, SMYD2, SNRPD3 | SAT1 597/4885ALDH1A1 1032/4885CYP3A4 4621/4885 |
| US-20170362217-A1 | Substituted Piperidine Compounds | SMYD3, SMYD2, SNRPD3 | SAT1 597/4885ALDH1A1 1032/4885CYP3A4 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.