Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | UQCRB | P14927 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19728622 | 0.84 | MCOLN3 (0.49) | CA2CA1ALDH1A1L3MBTL1KDM1A | |
| SCHEMBL13618709 | 0.74 | TRPV1 (0.44) | HSD17B2UQCRBTRPV1CA2CA1 | |
| SCHEMBL22388748 | 0.72 | TRPV1 (0.56) | TRPV1CA2CA1CHRM3ALDH1A1 | |
| SCHEMBL4741129 | 0.72 | TACR1 (0.51) | TRPV1CHRM3ALDH1A1NPC1RAB9A | |
| SCHEMBL25450282 | 0.71 | KCNK18 (0.44) | TRPV1CHRM3ALDH1A1L3MBTL1LMNA | |
| SCHEMBL5358209 | 0.71 | KIF11 (0.44) | CHRM3 | |
| SCHEMBL12632135 | 0.69 | CA1 (0.53) | TRPV1CA2CA1ALDH1A1NPC1 | |
| SCHEMBL4904785 | 0.68 | KIF11 (0.48) | ALDH1A1NPC1RAB9AL3MBTL1PLA2G1B | |
| SCHEMBL21226201 | 0.68 | ABCG2 (0.48) | NPC1RAB9ALMNAMCOLN3SMN1; SMN2 | |
| SCHEMBL29407530 | 0.68 | ABCG2 (0.48) | NPC1RAB9ALMNAMCOLN3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362263-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362263-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | PNKP, PLCB3, PLCB1 | HSD17B2 4086/4885UQCRB 4287/4885TRPV1 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.