Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19728623 | 0.84 | HSD17B2 (0.41) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL4533547 | 0.77 | KDM1A (0.60) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL31645593 | 0.77 | KDM1A (0.60) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL6864336 | 0.76 | FABP3 (0.46) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL16561359 | 0.76 | MCOLN3 (0.50) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL26621186 | 0.76 | MCOLN3 (0.50) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL9492832 | 0.74 | KEAP1 (0.52) | LMNACA12CA2CA9SMN1; SMN2 | |
| SCHEMBL27615436 | 0.73 | PTGS2 (0.65) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL16561334 | 0.73 | FABP4 (0.53) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL29446941 | 0.72 | KEAP1 (0.50) | CA12CA2CA9ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362263-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362263-A1 | PHOSPHORUS LIGANDS AND METHODS OF USE | PNKP, PLCB3, PLCB1 | MCOLN3 1458/4885LMNA 4198/4885CA12 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.