Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19728640 | 0.90 | KMT2A (0.50) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19728792 | 0.82 | KDM4E (0.47) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19728789 | 0.82 | KDM4E (0.47) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19728798 | 0.82 | STAT3 (0.55) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19728365 | 0.82 | KDM4E (0.50) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20912578 | 0.80 | STAT3 (0.49) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19728785 | 0.80 | KDM4E (0.45) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19729402 | 0.80 | LMNA (0.38) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19728641 | 0.80 | ALDH1A1 (0.44) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19729059 | 0.79 | STAT3 (0.47) | KMT2AALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017217441-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | 湧永製薬株式会社 | 2017-12-21 | — | — | WO | disclosed |