Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19729367 | 0.89 | PIK3CD (0.43) | PIK3CDNPBWR1MCHR1GPR119PIK3CA | |
| SCHEMBL19729369 | 0.83 | GPR119 (0.41) | PIK3CDNPBWR1MCHR1GPR119DPP4 | |
| SCHEMBL21341518 | 0.81 | GPR119 (0.39) | PIK3CDNPBWR1MCHR1GPR119PIK3CA | |
| SCHEMBL19729447 | 0.79 | SMN1; SMN2 (0.40) | NPBWR1MCHR1GPR119PDE4BUSP30 | |
| SCHEMBL5970964 | 0.77 | GPR119 (0.56) | NPBWR1MCHR1GPR119PDE4BKDM4E | |
| SCHEMBL2339564 | 0.76 | STS (0.51) | PIK3CDGPR119PIK3CAPIK3CBPIK3CG | |
| SCHEMBL2339872 | 0.76 | STS (0.51) | PIK3CDGPR119PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15696667 | 0.76 | GPR119 (0.49) | PIK3CDGPR119PIK3CAPIK3CBPIK3CG | |
| SCHEMBL22278273 | 0.76 | GPR119 (0.52) | PIK3CDGPR119PIK3CAPIK3CBPIK3CG | |
| SCHEMBL22278188 | 0.76 | GPR119 (0.52) | PIK3CDGPR119PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017217441-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | 湧永製薬株式会社 | 2017-12-21 | — | — | WO | disclosed |