Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19730216 | 0.95 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL19730228 | 0.95 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL29315894 | 0.92 | ALDH1A1 (0.54) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL29315898 | 0.92 | ALDH1A1 (0.54) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL21242234 | 0.92 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL21242530 | 0.92 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL13506252 | 0.92 | TSHR (0.61) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL19730231 | 0.91 | THRB (0.43) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL29315889 | 0.90 | THRB (0.55) | TSHRALDH1A1CYP3A4THRBHDAC1 | |
| SCHEMBL21242266 | 0.90 | TSHR (0.59) | TSHRALDH1A1CYP3A4THRBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170364025-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE INCLUDING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2017-12-21 | — | — | US | disclosed |