Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 6/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19730251 | 0.90 | AKR1B10 (0.43) | AKR1B10AKR1B1THRBMGLLLMNA | |
| SCHEMBL19730231 | 0.89 | THRB (0.43) | AKR1B10AKR1B1THRBMGLLALDH1A1 | |
| SCHEMBL19738422 | 0.88 | THRB (0.40) | AKR1B10AKR1B1THRBMGLLHCAR2 | |
| SCHEMBL19730225 | 0.88 | AKR1B1 (0.42) | AKR1B10AKR1B1THRBMGLLHCAR2 | |
| SCHEMBL19738395 | 0.87 | AKR1B10 (0.42) | AKR1B10AKR1B1THRBMGLLLMNA | |
| SCHEMBL19738373 | 0.86 | AKR1B10 (0.41) | AKR1B10AKR1B1THRBMGLLLMNA | |
| SCHEMBL19730223 | 0.86 | AKR1B1 (0.43) | AKR1B10AKR1B1THRBMGLLHCAR2 | |
| SCHEMBL19730230 | 0.84 | THRB (0.47) | AKR1B10AKR1B1THRBHCAR2LMNA | |
| SCHEMBL19730236 | 0.83 | THRB (0.46) | AKR1B10AKR1B1THRBHCAR2LMNA | |
| SCHEMBL19730219 | 0.83 | THRB (0.46) | AKR1B10AKR1B1THRBHCAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170364025-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE INCLUDING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2017-12-21 | — | — | US | disclosed |