Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2256514 | 0.88 | TLR8 (0.40) | CYP2A6CYP1A2ATMMEN1KMT2A | |
| SCHEMBL5748058 | 0.85 | KCNH2 (0.43) | TLR8 | |
| SCHEMBL2253153 | 0.85 | KCNH2 (0.43) | TLR8 | |
| SCHEMBL2253984 | 0.85 | KCNH2 (0.43) | TLR8 | |
| SCHEMBL2254059 | 0.83 | MEN1 (0.38) | CYP2A6CYP1A2ATMMEN1KMT2A | |
| SCHEMBL455936 | 0.83 | CYP2A6 (0.45) | CYP2A6CYP1A2KDM4EALDH1A1ATM | |
| SCHEMBL28010056 | 0.82 | TDP1 (0.37) | CYP2A6CYP1A2RAB9ATDP1NPC1 | |
| SCHEMBL2252289 | 0.81 | KCNH2 (0.40) | ATMMEN1KMT2ATLR8NPC1 | |
| SCHEMBL2256988 | 0.81 | KCNH2 (0.40) | ATMMEN1KMT2ATLR8NPC1 | |
| SCHEMBL5749119 | 0.81 | KCNH2 (0.40) | ATMMEN1KMT2ATLR8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107085033-A | N phenylnaphthalenes aminated compounds as MALDI matrix application | 中国科学院化学研究所 | 2017-08-22 | — | — | CN | disclosed |
| US-9469662-B2 | Process for preparing optically active biophosphinylalkanes | BASF SE (DE) | 2016-10-18 | — | — | US | disclosed |
| EP-1913007-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES | BASF SE (DE) | 2011-06-22 | — | — | EP | disclosed |
| US-20080242893-A1 | Process for Preparing Optically Active Diphosphanes | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-02 | — | — | US | disclosed |
| EP-1913007-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES | BASF SE (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007012655-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES | BASF SE (DE) | 2007-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242893-A1 | Process for Preparing Optically Active Diphosphanes | PHOSPHO1, DCTPP1, DCPS | CYP2A6 582/4885CYP1A2 1284/4885KDM4E 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.