Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19895673 | 0.93 | HPGD (0.35) | HPGDOPRM1OPRD1ALDH1A1GAA | |
| SCHEMBL21431255 | 0.86 | HDAC6 (0.38) | HPGDALDH1A1SLC6A1HDAC6SLC6A11 | |
| SCHEMBL21431166 | 0.86 | HDAC6 (0.38) | HPGDALDH1A1SLC6A1HDAC6SLC6A11 | |
| SCHEMBL19731704 | 0.85 | HPGD (0.37) | HPGDOPRM1OPRD1ALDH1A1GAA | |
| SCHEMBL22380926 | 0.84 | SLC6A11 (0.34) | ALDH1A1KMT2ASLC6A1SLC6A11CYP1A2 | |
| SCHEMBL12191613 | 0.83 | SMN1; SMN2 (0.33) | HPGDALDH1A1GAAKMT2AHDAC6 | |
| SCHEMBL27050962 | 0.83 | SLC6A1 (0.34) | ALDH1A1GAASLC6A1SLC6A11CYP1A2 | |
| SCHEMBL2820572 | 0.83 | SLC6A1 (0.34) | ALDH1A1GAASLC6A1SLC6A11CYP1A2 | |
| SCHEMBL16329608 | 0.83 | SLC6A1 (0.34) | ALDH1A1GAASLC6A1SLC6A11CYP1A2 | |
| SCHEMBL25764740 | 0.83 | SLC6A1 (0.34) | ALDH1A1GAASLC6A1SLC6A11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10890585-B2 | Method of immobilizing a cell on a support using compounds comprising a polyethylene glycol moiety | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2021-01-12 | — | — | US | disclosed |
| US-20170363624-A1 | METHOD OF IMMOBILIZING A CELL ON A SUPPORT USING COMPOUNDS COMPRISING A POLYETHYLENE GLYCOL MOIETY | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2017-12-21 | — | — | US | disclosed |