SCHEMBL19731823

SCHEMBL19731823

COc1ccc(O[C@H]2OC(COCc3ccccc3)[C@@H](O)C(OCc3ccccc3)C2O)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GJB2 P29033 3/20 0.47
▸ GJA1 P17302 1/20 0.47
▸ SLC6A2 P23975 2/20 0.45
▸ SSTR5 P35346 3/20 0.44
▸ SSTR4 P31391 3/20 0.43
▸ SSTR1 P30872 2/20 0.43
▸ SSTR2 P30874 2/20 0.43
▸ SSTR3 P32745 2/20 0.43
▸ SLC5A1 P13866 1/20 0.42
▸ SLC5A2 P31639 1/20 0.42
▸ NT5E P21589 1/20 0.42
▸ TACR2 P21452 1/20 0.41
▸ NPC1 O15118 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ PTPN2 P17706 1/20 0.40
▸ PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27001592 0.91 GJB2 (0.52) GJB2GJA1SLC6A2SSTR5SSTR4
SCHEMBL22073762 0.91 SSTR5 (0.46) GJB2GJA1SLC6A2SSTR5SSTR4
SCHEMBL22073053 0.91 GJB2 (0.49) GJB2GJA1SLC6A2SSTR5SSTR4
SCHEMBL7947474 0.89 GJB2 (0.54) GJB2GJA1SSTR5SSTR4SSTR1
SCHEMBL18523297 0.89 SLC6A2 (0.57) SLC6A2SLC5A1SLC5A2NPC1RAB9A
SCHEMBL15481400 0.89 SLC6A2 (0.57) SLC6A2SLC5A1SLC5A2NPC1RAB9A
SCHEMBL27473226 0.85 SLC5A1 (0.55) SLC6A2SLC5A1SLC5A2NPC1RAB9A
SCHEMBL27002578 0.85 GJB2 (0.42) GJB2GJA1SLC6A2SSTR5SSTR4
SCHEMBL29092324 0.85 GJB2 (0.42) GJB2GJA1SLC6A2SSTR5SSTR4
SCHEMBL24217572 0.84 GJB2 (0.54) GJB2GJA1SLC6A2SSTR5SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10336784-B2 Methods for modular synthesis of N-glycans and arrays thereof ACADEMIA SINICA (TW) 2019-07-02 — — US disclosed
US-20170362265-A1 METHODS FOR MODULAR SYNTHESIS OF N-GLYCANS AND ARRAYS THEREOF ACADEMIA SINICA (TW) 2017-12-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362265-A1 METHODS FOR MODULAR SYNTHESIS OF N-GLYCANS AND ARRAYS THEREOF SIGLEC7, SIGLEC9, CD4 GJB2 3462/4885GJA1 3238/4885SLC6A2 1768/4885
US-10336784-B2 Methods for modular synthesis of N-glycans and arrays thereof SIGLEC7, SIGLEC9, CD4 GJB2 3462/4885GJA1 3238/4885SLC6A2 1768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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