Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 6/20 | 0.54 |
| ▸ | GJA1 | P17302 | 4/20 | 0.54 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.45 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22073053 | 0.93 | GJB2 (0.49) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL22073762 | 0.89 | SSTR5 (0.46) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL19731823 | 0.89 | GJB2 (0.47) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL7947478 | 0.89 | SSTR1 (0.52) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL12136530 | 0.87 | GJB2 (0.49) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL27001592 | 0.87 | GJB2 (0.52) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL7942767 | 0.87 | GJB2 (0.44) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL7936603 | 0.87 | GJB2 (0.44) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL7944208 | 0.87 | GJB2 (0.44) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL7945562 | 0.87 | GJB2 (0.44) | GJB2GJA1SSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245902-B1 | USEFUL FOR PREPARING C-GLYCOSIDE ANALOGS OF GANGLIOSIDES, PEPTIDES, AND PROTEINS, AS WELL AS SYNTHETIC INTERMEDIATES USEFUL FOR THE PREPARATION OF THE PRECURSORS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2001-06-12 | — | — | US | disclosed |