SCHEMBL19731863

SCHEMBL19731863

COc1ccc(O[C@@H]2CC(OCc3ccccc3)[C@@H]3OC(c4ccccc4)OCC3O2)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 2/20 0.41
KCNA5 P22460 2/20 0.36
KDM1A O60341 1/20 0.35
PKM P14618 1/20 0.35
CYP3A4 P08684 3/20 0.33
MAPT P10636 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2D6 P10635 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1776705 0.87 KMT2A (0.50) L3MBTL1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL1776704 0.87 KMT2A (0.50) L3MBTL1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL19674474 0.87 KMT2A (0.50) L3MBTL1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL10755879 0.87 KMT2A (0.50) L3MBTL1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL10755871 0.87 KMT2A (0.50) L3MBTL1KMT2AMEN1ALDH1A1CYP3A4
SCHEMBL19731861 0.87 KMT2A (0.42) L3MBTL1KMT2AMEN1ALDH1A1KDM1A
SCHEMBL12302297 0.82 KMT2A (0.43) L3MBTL1KMT2AMEN1KCNA5KDM1A
SCHEMBL19726133 0.82 KMT2A (0.48) L3MBTL1KMT2AMEN1ALDH1A1KDM1A
SCHEMBL5094203 0.81 KMT2A (0.43) L3MBTL1KMT2AMEN1KCNA5KDM1A
SCHEMBL21708422 0.79 L3MBTL1 (0.61) L3MBTL1KMT2AMEN1ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10336784-B2 Methods for modular synthesis of N-glycans and arrays thereof ACADEMIA SINICA (TW) 2019-07-02 US disclosed
US-20170362265-A1 METHODS FOR MODULAR SYNTHESIS OF N-GLYCANS AND ARRAYS THEREOF ACADEMIA SINICA (TW) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362265-A1 METHODS FOR MODULAR SYNTHESIS OF N-GLYCANS AND ARRAYS THEREOF SIGLEC7, SIGLEC9, CD4 L3MBTL1 1587/4885KMT2A 3272/4885MEN1 1327/4885
US-10336784-B2 Methods for modular synthesis of N-glycans and arrays thereof SIGLEC7, SIGLEC9, CD4 L3MBTL1 1587/4885KMT2A 3272/4885MEN1 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.