SCHEMBL1776705

SCHEMBL1776705

COC1C[C@@H](OCc2ccccc2)[C@@H]2OC(c3ccccc3)OC[C@H]2O1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
ALDH1A1 P00352 1/20 0.47
PSEN1 P49768 3/20 0.36
PSEN2 P49810 3/20 0.36
APH1B Q8WW43 3/20 0.36
NCSTN Q92542 3/20 0.36
APH1A Q96BI3 3/20 0.36
PSENEN Q9NZ42 3/20 0.36
MAPT P10636 2/20 0.35
BCHE P06276 1/20 0.35
CYP2C19 P33261 1/20 0.35
SELP P16109 1/20 0.34
ADRA1A P35348 1/20 0.33
CYP1A2 P05177 1/20 0.33
PDE4D Q08499 1/20 0.33
CTSV O60911 1/20 0.33
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1776704 1.00 KMT2A (0.50) KMT2AMEN1L3MBTL1ALDH1A1PSEN1
SCHEMBL10755871 1.00 KMT2A (0.50) KMT2AMEN1L3MBTL1ALDH1A1PSEN1
SCHEMBL19674474 1.00 KMT2A (0.50) KMT2AMEN1L3MBTL1ALDH1A1PSEN1
SCHEMBL10755879 1.00 KMT2A (0.50) KMT2AMEN1L3MBTL1ALDH1A1PSEN1
SCHEMBL19731863 0.87 L3MBTL1 (0.44) KMT2AMEN1L3MBTL1ALDH1A1MAPT
Deoxyglucose SCHEMBL4587750 0.84 L3MBTL1 (0.41) KMT2AMEN1L3MBTL1ALDH1A1BCHE
SCHEMBL10907214 0.84 L3MBTL1 (0.49) KMT2AMEN1L3MBTL1ALDH1A1MAPT
SCHEMBL21090638 0.81 BCHE (0.39) L3MBTL1ALDH1A1PSEN1PSEN2APH1B
SCHEMBL22002346 0.81 L3MBTL1 (0.41) KMT2AMEN1L3MBTL1ALDH1A1SELP
SCHEMBL23742970 0.80 L3MBTL1 (0.41) KMT2AMEN1L3MBTL1ALDH1A1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7943584-B2 Medicinal composition containing diabetes remedy SANKYO COMPANY, LIMITED (JP) 2011-05-17 US disclosed
US-7632930-B2 Oligosaccharide derivative SANKYO COMPANY LIMITED (JP) 2009-12-15 US disclosed
US-20080194495-A1 Oligosaccharide Derivative HONDA TAKESHI 2008-08-14 US disclosed
US-7361744-B2 Oligosaccharide derivative SANKYO COMPANY LIMITED (JP) 2008-04-22 US disclosed
EP-1792620-A1 MEDICINAL COMPOSITION CONTAINING DIABETES REMEDY Sankyo Company, Limited (JP) 2007-06-06 EP disclosed
US-20060025350-A1 Oligosaccharide derivative SANKYO COMPANY, LIMITED (JP) 2006-02-02 US disclosed
EP-1589023-A1 OLIGOSACCHARIDE DERIVATIVE Sankyo Company, Limited (JP) 2005-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060025350-A1 Oligosaccharide derivative MAN1B1, FUT6, MAN2A1 KMT2A 3663/4885MEN1 366/4885L3MBTL1 2563/4885
US-20080194495-A1 Oligosaccharide Derivative MAN1B1, FUT6, MAN2A1 KMT2A 3663/4885MEN1 366/4885L3MBTL1 2563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.