Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12156787 | 1.00 | GRIK1 (0.35) | GRIK1GRIK2FPR2TSHR | |
| SCHEMBL1657367 | 0.81 | — | — | |
| SCHEMBL12190414 | 0.81 | — | — | |
| SCHEMBL12173791 | 0.81 | — | — | |
| SCHEMBL1657369 | 0.81 | — | — | |
| SCHEMBL12973841 | 0.81 | — | — | |
| SCHEMBL17930155 | 0.80 | FFAR1 (0.32) | — | |
| SCHEMBL1657182 | 0.80 | FFAR1 (0.32) | — | |
| SCHEMBL1657180 | 0.80 | FFAR1 (0.32) | — | |
| SCHEMBL27833980 | 0.80 | TRPA1 (0.36) | GRIK1GRIK2FPR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362277-A1 | CYCLOSPORINE ANALOGUE MIXTURES AND THEIR USE AS IMMUNOMODULATING AGENTS | ISOTECHNIKA INC. (CA) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362277-A1 | CYCLOSPORINE ANALOGUE MIXTURES AND THEIR USE AS IMMUNOMODULATING AGENTS | HLA-C, HLA-DRB1, HLA-B | GRIK1 4760/4885GRIK2 4677/4885FPR2 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.