SCHEMBL197329

SCHEMBL197329

CCC(CO)C(O)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9542808 0.84
SCHEMBL7712359 0.81 SLC1A3 (0.39)
SCHEMBL7712355 0.79 CA2 (0.39)
SCHEMBL7524695 0.78
SCHEMBL1850358 0.78 LMNA (0.35)
SCHEMBL7515469 0.74
SCHEMBL10585376 0.74
SCHEMBL7213464 0.74
SCHEMBL7509588 0.74 CA2 (0.41)
SCHEMBL27408784 0.74 CA2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0140865-A1 Enhanced 2-hydroxy-4-methylthiobutanoic acid composition and method of preparation Monsanto Company (US) 1985-05-08 EP claimed
US-12351549-B2 Agent for initiating a radical addition reaction and process using it ADISSEO FRANCE S.A.S. (FR) 2025-07-08 US disclosed
CN-119912371-A Reagent for initiating free radical addition reaction and method of use thereof 安迪苏法国联合股份有限公司 2025-05-02 CN disclosed
WO-2025052079-A1 PROCESS FOR THE SYNTHESIS OF METHIONINE AND ANALOGS THEREOF ADISSEO FRANCE S.A.S. (FR) 2025-03-13 WO disclosed
CN-119351518-A High-flux detection method of 2-hydroxy acid and application thereof 摩珈(上海)生物科技有限公司 2025-01-24 CN disclosed
US-20220127223-A1 AGENT FOR INITIATING A RADICAL ADDITION REACTION AND PROCESS USING IT ADISSEO FRANCE S.A.S. (FR) 2022-04-28 US disclosed
EP-3911628-A1 AGENT FOR INITIATING A RADICAL ADDITION REACTION AND PROCESS USING IT Adisseo France S.A.S. (FR) 2021-11-24 EP disclosed
CN-113286782-A Reagent for initiating free radical addition reaction and method of use thereof 安迪苏法国联合股份有限公司 2021-08-20 CN disclosed
WO-2020148509-A1 AGENT FOR INITIATING A RADICAL ADDITION REACTION AND PROCESS USING IT ADISSEO FRANCE S.A.S. (FR) 2020-07-23 WO disclosed
US-9828594-B2 Nitrilases, nucleic acids encoding them and methods for making and using them BASF ENZYMES LLC (US) 2017-11-28 US disclosed
EP-0832062-A1 CONTINUOUS HYDROLYSIS PROCESS FOR PREPARING 2-HYDROXY-4-METHYLTHIOBUTANOIC ACID OR SALTS THEREOF Novus International, Inc. (US) 1998-04-01 EP disclosed
WO-1996040630-A1 CONTINUOUS HYDROLYSIS PROCESS FOR PREPARING 2-HYDROXY-4-METHYLTHIOBUTANOIC ACID OR SALTS THEREOF NOVUS INTERNATIONAL, INC. (US) 1996-12-19 WO disclosed
US-5234696-A Mixture of powdered amino acids, keto acids and conjugates and salts thereof, compaction to remove air; nutritional treatment of chronic renal failure ABBOTT LABORATORIES (US) 1993-08-10 US disclosed
EP-0405295-B1 IMPROVED NUTRITIONAL FORMULATION FOR THE TREATMENT OF RENAL DISEASE ABBOTT LABORATORIES (US) 1993-07-14 EP disclosed
WO-1993012767-A1 METHOD OF PRODUCING AND TREATMENT WITH TABLET COMPOSITION ABBOTT LABORATORIES (US) 1993-07-08 WO disclosed
EP-0405295-A2 Improved nutritional formulation for the treatment of renal disease ABBOTT LABORATORIES (US) 1991-01-02 EP disclosed
US-4957938-A MIXTURE OF AMINO ACID SALTS FOR USE WITH LOW PROTEIN DIET ABBOTT LABORATORIES (US) 1990-09-18 US disclosed
EP-0143100-A2 Process for the preparation of liquid 2-hydroxy-methylthiobutyric acid MONSANTO COMPANY (US) 1985-05-29 EP disclosed
EP-0142488-A2 Liquid 2-hydroxy-methylthiobutyric acid and process for the preparation thereof MONSANTO COMPANY (US) 1985-05-22 EP disclosed
US-4000318-A LOWER ALKYL ESTER OF AMINO ACID COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1976-12-28 US disclosed