⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756105 | 0.86 | TSHR (0.71) | — | |
| SCHEMBL8927810 | 0.83 | — | — | |
| SCHEMBL31241576 | 0.83 | TSHR (0.68) | — | |
| SCHEMBL7509590 | 0.82 | CAMK2A (0.62) | — | |
| SCHEMBL7842665 | 0.82 | TSHR (0.60) | — | |
| SCHEMBL10815792 | 0.81 | TSHR (0.65) | — | |
| SCHEMBL6866613 | 0.81 | LMNA (0.78) | — | |
| SCHEMBL11651204 | 0.79 | TSHR (0.62) | — | |
| SCHEMBL2280524 | 0.78 | LMNA (0.65) | — | |
| SCHEMBL10482292 | 0.77 | LMNA (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12351549-B2 | Agent for initiating a radical addition reaction and process using it | ADISSEO FRANCE S.A.S. (FR) | 2025-07-08 | — | — | US | disclosed |
| CN-119912371-A | Reagent for initiating free radical addition reaction and method of use thereof | 安迪苏法国联合股份有限公司 | 2025-05-02 | — | — | CN | disclosed |
| WO-2025052079-A1 | PROCESS FOR THE SYNTHESIS OF METHIONINE AND ANALOGS THEREOF | ADISSEO FRANCE S.A.S. (FR) | 2025-03-13 | — | — | WO | disclosed |
| US-20220127223-A1 | AGENT FOR INITIATING A RADICAL ADDITION REACTION AND PROCESS USING IT | ADISSEO FRANCE S.A.S. (FR) | 2022-04-28 | — | — | US | disclosed |
| EP-3911628-A1 | AGENT FOR INITIATING A RADICAL ADDITION REACTION AND PROCESS USING IT | Adisseo France S.A.S. (FR) | 2021-11-24 | — | — | EP | disclosed |
| CN-113286782-A | Reagent for initiating free radical addition reaction and method of use thereof | 安迪苏法国联合股份有限公司 | 2021-08-20 | — | — | CN | disclosed |
| WO-2020148509-A1 | AGENT FOR INITIATING A RADICAL ADDITION REACTION AND PROCESS USING IT | ADISSEO FRANCE S.A.S. (FR) | 2020-07-23 | — | — | WO | disclosed |
| US-9828594-B2 | Nitrilases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2017-11-28 | — | — | US | disclosed |
| US-20160355801-A1 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORPORATION | 2016-12-08 | — | — | US | disclosed |
| US-9315792-B2 | Nitrilases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-6180359-B1 | HYDROLYSIS OF THE CORRESPONDING NITRILE | AVENTIS ANIMAL NUTRITION S.A. (FR) | 2001-01-30 | — | — | US | disclosed |
| WO-2000002852-A1 | METHOD FOR PREPARING HYDROXYMETHYLTHIOBUTYRIC ACID | AVENTIS ANIMAL NUTRITION S.A. (FR) | 2000-01-20 | — | — | WO | disclosed |
| WO-2000002853-A1 | METHOD FOR SEPARATING HYDROXYMETHYLTHIOBUTYRIC ACID | AVENTIS ANIMAL NUTRITION S.A. (FR) | 2000-01-20 | — | — | WO | disclosed |
| US-5234696-A | Mixture of powdered amino acids, keto acids and conjugates and salts thereof, compaction to remove air; nutritional treatment of chronic renal failure | ABBOTT LABORATORIES (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0405295-B1 | IMPROVED NUTRITIONAL FORMULATION FOR THE TREATMENT OF RENAL DISEASE | ABBOTT LABORATORIES (US) | 1993-07-14 | — | — | EP | disclosed |
| WO-1993012767-A1 | METHOD OF PRODUCING AND TREATMENT WITH TABLET COMPOSITION | ABBOTT LABORATORIES (US) | 1993-07-08 | — | — | WO | disclosed |
| EP-0405295-A2 | Improved nutritional formulation for the treatment of renal disease | ABBOTT LABORATORIES (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4957938-A | MIXTURE OF AMINO ACID SALTS FOR USE WITH LOW PROTEIN DIET | ABBOTT LABORATORIES (US) | 1990-09-18 | — | — | US | disclosed |
| US-4889950-A | Preparation of carboxylic esters | BASF AKTIENGESELLSCHAFT (DE) | 1989-12-26 | — | — | US | disclosed |
| US-4104196-A | Nonabsorbable antioxidant method | DYNAPOL (US) | 1978-08-01 | — | — | US | disclosed |